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Intraocular Melanoma (Melanoma of the Eye)

A rare cancer of melanocytes (cells that produce the pigment melanin) found in the eye.

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

About Melanoma of the Eye (Intraocular Melanoma)

Intraocular melanoma is a disease in which malignant (cancer) cells form in the tissues of the eye.

Intraocular melanoma begins in the middle of three layers of the wall of the eye. The outer layer includes the white sclera (the "white of the eye") and the clear cornea at the front of the eye. The inner layer has a lining of nerve tissue, called the retina, which senses light and sends images along the optic nerve to the brain.

The middle layer, where intraocular melanoma forms, is called the uvea or uveal tract, and has three main parts:


The iris is the colored area at the front of the eye (the "eye color"). It can be seen through the clear cornea. The pupil is in the center of the iris and it changes size to let more or less light into the eye. Intraocular melanoma of the iris is usually a small tumor that grows slowly and rarely spreads to other parts of the body... Read more about Intraocular Melanoma

What works? Research summarized

Evidence reviews

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This study found that the effectiveness of fibrin sealants do not appear to vary according to surgical procedures with regard to reducing the risk of seroma or haematoma.

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Summaries for consumers

Intraocular (Uveal) Melanoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of intraocular (uveal) melanoma.

Melanoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of melanoma.

Cancer-Related Post-traumatic Stress (PDQ®): Patient Version

Cancer-related post-traumatic stress can occur any time from diagnosis to after treatment ends. Shock, fear, helplessness, or horror can be felt by cancer patients and lead to cancer-related post-traumatic stress. Learn about the causes and ways doctors can help manage these symptoms of distress in this expert-reviewed summary.

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Terms to know

Eyes are the organs of vision. They detect light and convert it.
Within the eyeball.
A pigment that gives color to skin and eyes and helps protect it from damage by ultraviolet light.
A cell in the skin and eyes that produces and contains the pigment called melanin.
The middle layer of the wall of the eye. The uvea has 3 main parts: (1) the choroid (the tissue layer filled with blood vessels); (2) the ciliary body (the ring of muscle tissue that changes the size of the pupil and the shape of the lens); and (3) the iris (the colored part of the eye). Also called uveal tract.

More about Intraocular Melanoma

Photo of an adult

Also called: Melanoma of the uvea, Eye melanoma, Ocular melanoma, Uveal melanoma

Other terms to know: See all 5
Eye, Intraocular, Melanin

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