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Nausea

A feeling of sickness or discomfort in the stomach that may come with an urge to vomit.

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

What works? Research summarized

Evidence reviews

Levomepromazine for the treatment of nausea and vomiting in people with advanced disease

This is an update of the review published in 2013. Nausea (feeling sick) and vomiting (being sick) are common and unpleasant symptoms that are often experienced by people with advanced disease. There are several different drug therapies which are available to treat these symptoms, known as antiemetics. Levomepromazine was originally used to treat schizophrenia but is also used to control nausea and vomiting. It can be given as a tablet or as an injection.

Droperidol for the treatment of nausea and vomiting (sickness) in people with advanced disease

Nausea (a feeling of sickness) and vomiting are common and distressing symptoms for people with advanced cancer and other life‐threatening illnesses. Several medications to control these symptoms are available. Droperidol is one example, which has been used to try to prevent or treat nausea and vomiting for people having surgery or chemotherapy. In our search updated in November 2013 we found no randomised studies of droperidol for the treatment of nausea or vomiting for people receiving palliative care or suffering from an incurable progressive medical condition. Several studies reported on the use of droperidol for the prevention of nausea and vomiting associated with chemotherapy. Further studies are needed to find out which medications are most suitable to treat nausea and vomiting in palliative care.

Long-term Use of Ondansetron, Dolasetron and Granisetron for the Prevention of Nausea and Vomiting: A Review of the Clinical Effectiveness and Safety [Internet]

The purpose of this review is to provide evidence on the comparative clinical effectiveness and safety of the long-term use (> 5 days) of serotonin receptor antagonists (5-HT3RAs) for the prevention of nausea and vomiting.

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Summaries for consumers

Levomepromazine for the treatment of nausea and vomiting in people with advanced disease

This is an update of the review published in 2013. Nausea (feeling sick) and vomiting (being sick) are common and unpleasant symptoms that are often experienced by people with advanced disease. There are several different drug therapies which are available to treat these symptoms, known as antiemetics. Levomepromazine was originally used to treat schizophrenia but is also used to control nausea and vomiting. It can be given as a tablet or as an injection.

Droperidol for the treatment of nausea and vomiting (sickness) in people with advanced disease

Nausea (a feeling of sickness) and vomiting are common and distressing symptoms for people with advanced cancer and other life‐threatening illnesses. Several medications to control these symptoms are available. Droperidol is one example, which has been used to try to prevent or treat nausea and vomiting for people having surgery or chemotherapy. In our search updated in November 2013 we found no randomised studies of droperidol for the treatment of nausea or vomiting for people receiving palliative care or suffering from an incurable progressive medical condition. Several studies reported on the use of droperidol for the prevention of nausea and vomiting associated with chemotherapy. Further studies are needed to find out which medications are most suitable to treat nausea and vomiting in palliative care.

Interventions for nausea and vomiting in early pregnancy

Nausea, retching or dry heaving, and vomiting in early pregnancy are very common and can be very distressing for women. Many treatments are available to women with 'morning sickness', including drugs and complementary and alternative therapies. Because of concerns that taking medications may adversely affect the development of the fetus, this review aimed to examine if these treatments have been found to be effective and safe.

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More about Nausea

Photo of an adult woman

Other terms to know:
Stomach, Vomiting

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