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Mitral Valve Prolapse (MVP)

Mitral valve prolapse (MVP) is a condition in which the heart's mitral valve doesn't work well. The flaps of the valve are "floppy" and don't close tightly. These flaps normally help seal or open the valve.

PubMed Health Glossary
(Source: NIH - National Heart, Lung, and Blood Institute)

About Mitral Valve Prolapse (MVP)

Mitral (MI-tral) valve prolapse (MVP) is a condition in which the heart's mitral valve doesn't work well. The flaps of the valve are "floppy" and don't close tightly. These flaps normally help seal or open the valve.

Much of the time, MVP doesn't cause any problems. Rarely, blood can leak the wrong way through the floppy valve. This can lead to palpitations, shortness of breath, chest pain, and other symptoms. (Palpitations are feelings that your heart is skipping a beat, fluttering, or beating too hard or too fast.)

Normal Mitral Valve

The mitral valve controls blood flow between the upper and lower chambers of the left side of the heart. The upper chamber is called the left atrium (AY-tree-um). The lower chamber is called the left ventricle (VEN-trih-kul).

The mitral valve allows blood to flow from the left atrium into the left ventricle, but not back the other way. The heart also has a... Read more about Mitral Valve Prolapse

What works? Research summarized

Evidence reviews

Systematic review of robotic minimally invasive mitral valve surgery

BACKGROUND: Robotic telemanipulators have evolved to assist the challenges of minimally invasive mitral valve surgery (MVS). A systematic review was performed to provide a synopsis of the literature, focusing on clinical outcomes and cost-effectiveness.

Pharmacotherapy in the treatment of mitral regurgitation: a systematic review

BACKGROUND AND AIM OF THE STUDY: Chronic mitral regurgitation (MR) causes volume overload on the left ventricle and, if uncorrected, will over time lead to left ventricular remodeling and heart failure. The benefits of angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs) in primary MR are not well defined.

Routine echocardiography in the management of stroke and transient ischaemic attack: a systematic review and economic evaluation

Study found that, transthoracic echocardiography in second harmonic imaging mode is a cost-effective use of NHS resources in those cases where clinicians deem it the most appropriate method of testing to identify cardiac sources of stroke and transient ischaemic attack. However, the study highlights that there is a lack of evidence in several areas and the results of the economic evaluation should be treated with caution.

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Terms to know

Atria
The chambers of the heart, to which the blood returns from the circulation.
Cardiac Valves (Heart Valves)
Any of the four heart valves that regulate the flow of blood through the chambers of the heart.
Heart
The hollow, muscular organ that maintains the circulation of the blood.
Heart Ventricles
The lower right and left chambers of the heart.
Mitral Valve
Valve between the left atrium and left ventricle of the heart.
Palpitations
Palpitations are feelings that your heart is skipping a beat, fluttering, or beating too hard or too fast.
Tricuspid Valve
The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.

More about Mitral Valve Prolapse

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Other terms to know: See all 7
Atria, Cardiac Valves (Heart Valves), Heart

Related articles:
How the Heart Works

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