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Endocarditis

Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves.

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(Source: Wikipedia)

What works? Research summarized

Evidence reviews

Antibiotics for the prevention of bacterial endocarditis (severe infection or inflammation of the lining of the heart chambers) in dentistry

This review, carried out by authors of the Cochrane Oral Health Group, has been produced to determine whether people at increased risk of bacterial endocarditis, a severe infection or inflammation of the lining of the heart chambers, should routinely take antibiotics before invasive dental procedures in order to reduce the incidence of endocarditis, the number of deaths, and the amount of serious illness this group of people experiences.

Antibiotic therapy for treatment of infective endocarditis

We aimed to assess the existing evidence about the clinical benefits and harms of different antibiotics regimens used to treat people with infective endocarditis.

Prophylaxis Against Infective Endocarditis: Antimicrobial Prophylaxis Against Infective Endocarditis in Adults and Children Undergoing Interventional Procedures [Internet]

Infective endocarditis (IE) is a rare condition with significant morbidity and mortality. It may arise following bacteraemia in a patient with a predisposing cardiac lesion. In an attempt to prevent this disease, over the past 50 years, at-risk patients have been given antibiotic prophylaxis before dental and certain non-dental interventional procedures.

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Summaries for consumers

Antibiotics for the prevention of bacterial endocarditis (severe infection or inflammation of the lining of the heart chambers) in dentistry

This review, carried out by authors of the Cochrane Oral Health Group, has been produced to determine whether people at increased risk of bacterial endocarditis, a severe infection or inflammation of the lining of the heart chambers, should routinely take antibiotics before invasive dental procedures in order to reduce the incidence of endocarditis, the number of deaths, and the amount of serious illness this group of people experiences.

Antibiotic therapy for treatment of infective endocarditis

We aimed to assess the existing evidence about the clinical benefits and harms of different antibiotics regimens used to treat people with infective endocarditis.

Injectable gold for treating rheumatoid arthritis

Although its use can be limited by the incidence of serious harms, injectable gold has an important clinically and statistically significant benefit in the short term treatment of patients with rheumatoid arthritis.

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Terms to know

Cardiac Valves (Heart Valves)
Any of the four heart valves that regulate the flow of blood through the chambers of the heart.
Endocardium
The endocardium is the innermost layer of tissue that lines the chambers of the heart.
Heart
The hollow, muscular organ that maintains the circulation of the blood.
Inflammation
Redness, swelling, pain, and/or a feeling of heat in an area of the body. This is a protective reaction to injury, disease, or irritation of the tissues.

More about Endocarditis

Photo of an adult

See Also: Infective Endocarditis

Other terms to know: See all 4
Cardiac Valves (Heart Valves), Endocardium, Heart

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