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Clinical Trial

A type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called clinical study.

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

Clinical Trials

Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. These studies also may show which medical approaches work best for certain illnesses or groups of people. Clinical trials produce the best data available for health care decisionmaking.

The purpose of clinical trials is research, so the studies follow strict scientific standards. These standards protect patients and help produce reliable study results.

Clinical trials are one of the final stages of a long and careful research process. The process often begins in a laboratory (lab), where scientists first develop and test new ideas.

If an approach seems promising, the next step may involve animal testing. This shows how the approach affects a living body and whether it's harmful. However, an approach that works well in the lab or animals doesn't always work well... Read more about Clinical Trial NIH - National Heart, Lung, and Blood Institute

Terms to know

CONSORT Statement
CONSORT (Consolidated Standards Of Reporting Trials) minimum set of recommendations for reporting randomized...
Clinical Trial Protocol
The written description of a clinical study. It includes the study's objectives, design, and methods. It may...
Phase I Trial
The first step in testing a new treatment in humans. These studies test the best way to give a new treatment...
Phase II Trial
A trial to study response to a new treatment and the effectiveness of the treatment compared with the standar...
Phase III Trial
A study to compare the results of people taking a new treatment with the results of people taking the standar...
Phase IV Trial
A type of clinical trial that studies the side effects of a treatment after it has been approved and is being...
Randomized Control Trial (RCT)
A study in which the participants are assigned by chance to separate groups; neither the researchers nor the...

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Terms to know

CONSORT Statement
CONSORT (Consolidated Standards Of Reporting Trials) minimum set of recommendations for reporting randomized...
Clinical Trial Protocol
The written description of a clinical study. It includes the study's objectives, design, and methods. It may...
Phase I Trial
The first step in testing a new treatment in humans. These studies test the best way to give a new treatment...
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