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Drospirenone and Estradiol

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

By mouth

Drospirenone and estradiol combination is used to treat moderate to severe hot flashes and other symptoms of menopause or low amounts of estrogen in women… Read more

Brand names include: Angeliq

By mouth

Drospirenone and ethinyl estradiol combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol… Read more

Brand names include: Drospirenone-Ethinyl Estradiol, Gianvi

Drug classes About this
Estrogen/Progestin Combination, Hormonal Contraceptive, Monophasic Contraceptive Combination
Combinations including this drug

What works? Research summarized

Evidence reviews

Birth control pills with drospirenone for treating premenstrual syndrome

Premenstrual syndrome (PMS) is a common problem. A severe form is called premenstrual dysphoric disorder (PMDD). Birth control pills with the hormones progestin and estrogen have been studied for treating such symptoms. A birth control pill with the progestin drospirenone may work better than other such pills. A drospirenone pill with low estrogen was approved for treating PMDD, the severe form of PMS, in women who use birth control pills.

Differences in effectiveness and adverse effects between different types of progestogens combined with ethinyl oestradiol (combined contraceptive pill)

Combined oral contraceptives (COC) have an oestrogen and a progestogen component. The type of progestogen and/or amount of oestrogen or progestogen can vary per pack of oral contraceptive pills. The objective of this review was to compare currently available low‐dose COCs containing different progestogens in terms of pregnancy prevention, bleeding pattern, side effects and discontinuation rates.

Drug Class Review: Hormone Therapy for Postmenopausal Women or Women in the Menopausal Transition Stage: Final Report Update # 3 [Internet]

Estrogen was approved as a hormone supplement in the 1940's to treat estrogen withdrawal symptoms in menopausal women. Estrogen production declines in women when ovarian function changes with aging or after surgical removal of the ovaries. This drop in estrogen levels can trigger a vasomotor response resulting in a sensation of flushing and sweating that interferes with function and sleep (hot flashes or flushes). Studies conducted in recent years have identified additional health benefits of postmenopausal estrogen besides symptom management (osteoporosis) as well as potential harms (cardiovascular disease, breast cancer, and cholecystitis). The purpose of this review was to compare the efficacy and adverse effects of different estrogens.

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Summaries for consumers

Birth control pills with drospirenone for treating premenstrual syndrome

Premenstrual syndrome (PMS) is a common problem. A severe form is called premenstrual dysphoric disorder (PMDD). Birth control pills with the hormones progestin and estrogen have been studied for treating such symptoms. A birth control pill with the progestin drospirenone may work better than other such pills. A drospirenone pill with low estrogen was approved for treating PMDD, the severe form of PMS, in women who use birth control pills.

Differences in effectiveness and adverse effects between different types of progestogens combined with ethinyl oestradiol (combined contraceptive pill)

Combined oral contraceptives (COC) have an oestrogen and a progestogen component. The type of progestogen and/or amount of oestrogen or progestogen can vary per pack of oral contraceptive pills. The objective of this review was to compare currently available low‐dose COCs containing different progestogens in terms of pregnancy prevention, bleeding pattern, side effects and discontinuation rates.

Which birth control pills can help reduce acne?

Using birth control pills as a form of contraception can improve the complexion of girls and women who have acne. Certain types of pills might be somewhat more effective in treating acne than others. But the differences are small.

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