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Zonisamide (By mouth)

Treats partial seizures.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Zonisamide is used together with other medicines to control partial seizures (convulsions) in the treatment of epilepsy. This medicine is an anticonvulsant that works in the brain to stop seizures. This medicine is available only with your doctor's prescription… Read more
Brand names include
Zonegran
Drug classes About this
Anticonvulsant

What works? Research summarized

Evidence reviews

Zonisamide for neuropathic pain in adults

Neuropathic pain can arise from damage to nerves and injury to the central nervous system. It is different from pain messages carried along healthy nerves from damaged tissue (a fall, or cut, or arthritic knee). Neuropathic pain is treated by different medicines than those used for pain from damaged tissue. Medicines like paracetamol or ibuprofen are not usually effective in neuropathic pain, while medicines that are sometimes used to treat depression or epilepsy can be very effective in some people with neuropathic pain.

Zonisamide add‐on for drug‐resistant partial epilepsy

Zonisamide in combination with another antiepileptic drug can reduce seizures, but with some adverse effects.

Use of zonisamide for the treatment of essential tremor

The authors of this review tried to assess the effectiveness and safety of zonisamide in people (16 years or older) with essential tremor.

See all (31)

Summaries for consumers

Zonisamide for neuropathic pain in adults

Neuropathic pain can arise from damage to nerves and injury to the central nervous system. It is different from pain messages carried along healthy nerves from damaged tissue (a fall, or cut, or arthritic knee). Neuropathic pain is treated by different medicines than those used for pain from damaged tissue. Medicines like paracetamol or ibuprofen are not usually effective in neuropathic pain, while medicines that are sometimes used to treat depression or epilepsy can be very effective in some people with neuropathic pain.

Zonisamide add‐on for drug‐resistant partial epilepsy

Zonisamide in combination with another antiepileptic drug can reduce seizures, but with some adverse effects.

Use of zonisamide for the treatment of essential tremor

The authors of this review tried to assess the effectiveness and safety of zonisamide in people (16 years or older) with essential tremor.

See all (11)

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