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Ulipristal (By mouth)

Prevents pregnancy. This medicine is an emergency contraceptive pill.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Ulipristal is an emergency contraceptive pill that is used to prevent pregnancy after unprotected sex or after failure of another birth control method. It works by preventing or delaying the release of a woman's egg from the ovary (ovulation). It may also prevent the attachment of the woman's egg to the wall of the uterus (womb). This medicine should not be used as a regular birth control method.… Read more
Brand names include
Ella
Drug classes About this
Contraceptive

What works? Research summarized

Evidence reviews

Ulipristal Acetate (Fibristal) (5 mg Tablets): Treatment of Moderate to Severe Signs and Symptoms of Uterine Fibroids in Adult Women of Reproductive Age Who are Eligible for Surgery. The Duration of Treatment is Limited to Three Months [Internet]

The objective of this systematic review was to evaluate the beneficial and harmful effects of ulipristal acetate 5 mg for the treatment of the signs or symptoms due to uterine fibroids in adult women of reproductive age who are eligible for surgical intervention.

Progesterone receptor modulators for endometriosis

Researchers in the Cochrane Collaboration reviewed evidence on the effectiveness and safety of progesterone receptor modulators for women with endometriosis.

Preoperative medical therapy before surgery for uterine fibroids

We investigated if giving drugs before surgery for uterine fibroids improves outcomes.

See all (7)

Summaries for consumers

Uterine fibroids: When is treatment with hormones considered?

Female sex hormones play an important role in fibroid growth. This makes it possible to shrink fibroids with hormone therapy. The hormones can be used to relieve symptoms or to help prepare for surgery. Some hormone therapies can be used to temporarily relieve heavy menstrual bleeding and period pain. These treatments can also shrink fibroids, but they can't make them disappear completely. Hormones are usually only used for a limited amount of time because of the risk of side effects. But the therapy only works for as long as it is used, so the fibroids may grow again once it is stopped. Hormone therapy is most commonly used to shrink fibroids before surgery. It may also be an option for women just before menopause – or for women who, for whatever reason, can’t have surgery. The different hormone therapies include: GnRH analogues (injections or nasal sprays)Progestins (hormonal intrauterine device and progestin-only pills)Progestin and estrogen combinations (combination birth control pills)Ulipristal acetate (the drug used in the “morning-after pill”)

Progesterone receptor modulators for endometriosis

Researchers in the Cochrane Collaboration reviewed evidence on the effectiveness and safety of progesterone receptor modulators for women with endometriosis.

Preoperative medical therapy before surgery for uterine fibroids

We investigated if giving drugs before surgery for uterine fibroids improves outcomes.

See all (7)

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