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Sevoflurane (By breathing)

Causes you to become unconscious (fall asleep) before having surgery. This medicine is a type of anesthesia.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Sevoflurane belongs to the group of medicines known as general anesthetics. Sevoflurane is used to cause general anesthesia (loss of consciousness) before and during surgery. It is inhaled (breathed in). Although sevoflurane can be used by itself, combinations of anesthetics are often used together. This helps produce more effective anesthesia in some patients. General anesthetics are given only… Read more
Brand names include
Amerinet Choice Sevoflurane, Sojourn, Ultane, Ultane Amerinet, Ultane Novation
Drug classes About this
Volatile Liquid

What works? Research summarized

Evidence reviews

High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia

We reviewed the evidence from randomized controlled trials comparing high initial concentrations of sevoflurane with low initial concentrations to see whether the evidence supports use of high initial concentrations to reduce induction times and complications for inhalational induction of anaesthesia. This update of a review first published in 2013 is current to February 2016.

Agitation in children after sevoflurane anaesthesia

We reviewed the evidence looking at how often children wake up agitated after a sevoflurane general anaesthetic compared with other general anaesthetics. We also reviewed evidence looking at the effects of other treatments (e.g. a medication given during the anaesthetic, the presence of a parent when a child wakes up) on how often children wake up agitated after receiving a sevoflurane anaesthetic.

Sevoflurane maintenance in children: a systematic review

Bibliographic details: Sun JH, Han N, Wu XY.  Sevoflurane maintenance in children: a systematic review. Chinese Journal of Evidence-Based Medicine 2008; 8(11): 988-996

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Summaries for consumers

High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia

We reviewed the evidence from randomized controlled trials comparing high initial concentrations of sevoflurane with low initial concentrations to see whether the evidence supports use of high initial concentrations to reduce induction times and complications for inhalational induction of anaesthesia. This update of a review first published in 2013 is current to February 2016.

Agitation in children after sevoflurane anaesthesia

We reviewed the evidence looking at how often children wake up agitated after a sevoflurane general anaesthetic compared with other general anaesthetics. We also reviewed evidence looking at the effects of other treatments (e.g. a medication given during the anaesthetic, the presence of a parent when a child wakes up) on how often children wake up agitated after receiving a sevoflurane anaesthetic.

Anaesthetic drugs for cardioversion

Electrical cardioversion is a procedure by which pads on the chest aim to return the heart to a normal rhythm following disturbances. This procedure is painful and can be distressing for the patient; therefore drugs are used to make patients unaware of the procedure. We aimed to compare the safety and effectiveness of the drugs used in electrical cardioversion.

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