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Saxagliptin (By mouth)

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Saxagliptin is used with proper diet and exercise to treat high blood sugar (glucose) levels in patients with type 2 diabetes. Saxagliptin helps to control blood sugar levels by making the pancreas gland release more insulin. It also signals the liver to stop producing sugar when there is too much sugar in the blood. This medicine does not help patients who have insulin-dependent or type 1 Read more
Brand names include
Onglyza
Drug classes About this
Antidiabetic
Combinations including this drug

What works? Research summarized

Evidence reviews

Saxagliptin -- Benefit Assessment According to §35a Social Code Book V [Internet]

The benefit assessment of saxagliptin was conducted according to the approval for the following therapeutic indication: treatment of adult patients with type 2 diabetes mellitus.

Saxagliptin (New Therapeutic Indication) -- Benefit Assessment According to §35a Social Code Book V [Internet]

The aim of this report is to assess the added benefit of saxagliptin in comparison with the appropriate comparator therapy (ACT) for the treatment of adult patients aged 18 years and older with type 2 diabetes mellitus for the therapeutic indication of the monotherapy that was newly approved in July 2013:

Saxagliptin / Metformin (New Therapeutic Indication) -- Benefit Assessment According to §35a Social Code Book V [Internet]

The benefit assessment was conducted for the new therapeutic indication of saxagliptin / metformin (wording in the Summary of Product Characteristics [SPC]):

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Summaries for consumers

Fixed combination of saxagliptin and metformin (Komboglyze) for the treatment of type 2 diabetes: Overview

The fixed combination of saxagliptin and metformin (trade name: Komboglyze) has been approved in Germany since November 2011 for the treatment of type 2 diabetes in adults who can't lower high blood sugar levels enough through exercise and diet alone.

Saxagliptin (Onglyza) for type 2 diabetes: Assessment of the study 'SAVOR-TIMI 53'

Saxagliptin (trade name: Onglyza) has been approved in Germany since October 2009 for the treatment of type 2 diabetes in adults who cannot lower high blood sugar levels enough through exercise and diet alone.

Saxagliptin (Onglyza) for type 2 diabetes: Overview

Saxagliptin (trade name: Onglyza) has been approved in Germany since October 2009 for the treatment of type 2 diabetes in adults who cannot lower blood sugar levels enough through exercise and diet alone.

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