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Rosuvastatin (By mouth)

Treats high cholesterol and triglyceride levels. May reduce the risk of heart attack, stroke, and related health conditions. This medicine is a statin.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Rosuvastatin is used together with a proper diet to lower cholesterol and triglycerides (fats) in the blood. This medicine may help prevent or slow down medical problems, like atherosclerosis (hardening of the arteries), that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart… Read more
Brand names include
Crestor
Drug classes About this
Antihyperlipidemic

What works? Research summarized

Evidence reviews

The effect of rosuvastatin on cholesterol

Rosuvastatin (Crestor) is one of the most potent statins and is currently widely prescribed. It is therefore important to know how much rosuvastatin lowers cholesterol. We searched for all the trial evidence from trials of three to 12 week duration reporting the effect of rosuvastatin on cholesterol. We found 108 trials involving 19,596 participants. Based on an informal comparison with atorvastatin three‐fold lower doses of rosuvastatin are needed to lower cholesterol by the same amount. This review cannot be used to assess harms of rosuvastatin, because of the short duration of these trials and the high risk of bias for this outcome; adverse effects were only reported in 10 of the 18 trials that could be used to assess harms.

Do statins prevent kidney failure in adults after surgery where cardiac bypass is used?

Heart surgeries are performed routinely in developed countries and their safety has increased significantly. However, heart surgery is still associated with complications. Of those, kidney failure is of great importance; and patients whose kidneys fail after a heart operation are more likely to have other health problems. Preventing kidney failure after heart surgery is therefore a major health issue.

Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy

We reviewed pharmacological interventions for treating heart failure in people with Chagas cardiomyopathy.

See all (108)

Summaries for consumers

The effect of rosuvastatin on cholesterol

Rosuvastatin (Crestor) is one of the most potent statins and is currently widely prescribed. It is therefore important to know how much rosuvastatin lowers cholesterol. We searched for all the trial evidence from trials of three to 12 week duration reporting the effect of rosuvastatin on cholesterol. We found 108 trials involving 19,596 participants. Based on an informal comparison with atorvastatin three‐fold lower doses of rosuvastatin are needed to lower cholesterol by the same amount. This review cannot be used to assess harms of rosuvastatin, because of the short duration of these trials and the high risk of bias for this outcome; adverse effects were only reported in 10 of the 18 trials that could be used to assess harms.

Do statins prevent kidney failure in adults after surgery where cardiac bypass is used?

Heart surgeries are performed routinely in developed countries and their safety has increased significantly. However, heart surgery is still associated with complications. Of those, kidney failure is of great importance; and patients whose kidneys fail after a heart operation are more likely to have other health problems. Preventing kidney failure after heart surgery is therefore a major health issue.

Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy

We reviewed pharmacological interventions for treating heart failure in people with Chagas cardiomyopathy.

See all (8)

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