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Micromedex DrugNotes [Internet]. Truven Health Analytics, an IBM company; 1974-2017.

Micromedex DrugNotes [Internet].

Phenyltoloxamine/Magnesium Salicylate (By mouth)

Phenyltoloxamine (fen-il-tol-OX-a-meen), Magnesium Salicylate (mag-NEE-zee-um sa-LIS-i-late)

Published: April 1, 2017.

Treats arthritis pain and swelling.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to phenyltoloxamine or aspirin, or if you have kidney disease, heart block, chickenpox, the flu, a viral infection, a bleeding disorder, or a history of stomach bleeding.

How to Use This Medicine


  • Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
  • It is best to take this medicine with food or milk.
  • Measure the oral liquid medicine with a marked measuring spoon or medicine cup.
  • Never share your medicine with anyone.

If a dose is missed:

  • If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
  • Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using blood thinners (Coumadin®), danaparoid (Orgaran®), heparin, methotrexate (Rheumatrex®), or medicines for glaucoma such as acetazolamide (Diamox®), brinzolamide (Azopt®), dichlorphenamide (Daranide®), dorzolamide (Trusopt®), or methazolamide (Neptazane®).
  • Make sure your doctor knows if you are using any medicines that make you sleepy (such as sleeping pills, cold and allergy medicine, narcotic pain relievers, or sedatives), or if you have received a chickenpox vaccine (Varivax®) within the past 6 weeks.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, high blood pressure, diabetes, glaucoma, asthma, or problems with urination.
  • Do not give this medicine to a child or teenager who has or recently had the flu or chickenpox. This medicine may cause Reye's syndrome in a child who has a viral infection or has just recovered from one. Reye's syndrome is a dangerous condition that can cause brain damage or death if not treated promptly.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Bloody, or black, tarry stools
  • Change in how much or how often you urinate
  • Fast or slow heartbeat, rapid breathing, extreme weakness, sweating, warmth or flushing of the skin
  • Lightheadedness or fainting
  • Ringing in your ears
  • Vomiting material that looks like coffee grounds

If you notice these less serious side effects, talk with your doctor:

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

© 2017 Truven Health Analytics LLC Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.

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