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Olopatadine (Into the nose)

Treats stuffy or runny nose caused by allergic rhinitis (hay fever).

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Olopatadine nasal spray is used to treat the symptoms of seasonal (short-term) allergic rhinitis (hay fever), such as sneezing, itchy or runny nose, or itchy eyes. It is an antihistamine and works by preventing the release of histamine in the body. Olopatadine will also block the effects of histamine, which prevents the allergic symptoms. This medicine is available only with your doctor's… Read more
Brand names include
Patanase
Other forms
Into the eye
Drug classes About this
Nasal Agent

What works? Research summarized

Evidence reviews

Olopatadine for the Treatment of Allergic Conjunctivitis: A Review of the Clinical Efficacy, Safety, and Cost-Effectiveness [Internet]

This Rapid Response report aims to review the clinical- and cost-effectiveness of olopatadine for the treatment of allergic conjunctivitis. This is an update to the previous CADTH Rapid Response review.

Standardized Allergenic Extract, Timothy grass (Phleum pratense) (GRASTEK) (sublingual tablet 2,800 BAU) [Internet]

The objective is to conduct a systematic review of the beneficial and harmful effects of Timothy grass (Phleum pratense) standardized allergenic extract (PPAE; brand name Grastek) 2,800 BAU, for the treatment of Timothy and related grass pollen–induced allergic rhinitis (AR), with or without conjunctivitis, in adults and children aged five years and older.

Drug Class Review: Newer Antihistamines: Final Report Update 2 [Internet]

Antihistamines inhibit the effects of histamine at H1 receptors. They have a number of clinical indications including allergic conditions (e.g., rhinitis, dermatoses, atopic dermatitis, contact dermatitis, allergic conjunctivitis, hypersensitivity reactions to drugs, mild transfusion reactions, and urticaria), chronic idiopathic urticaria (CIU), motion sickness, vertigo, and insomnia.

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Summaries for consumers

Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis

Are treatments with eye drops of antihistamines and mast cell stabilisers, alone or in combination, effective and safe in people with seasonal and allergic conjunctivitis? The main outcome measure was eye symptoms reported by participants, including eye itching, irritation (burning sensation), watering eyes (tearing), and photophobia (dislike of light). We found 30 trials.

Comparing New Antihistamines

How do newer antihistamines compare in treating allergic rhinitis?

PubMed Health Blog...

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