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Nifedipine (By mouth)

Treats high blood pressure and angina (chest pain). This medicine is a calcium channel blocker.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or Read more
Brand names include
Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL
Drug classes About this
Antianginal, Antihypertensive, Antimigraine, Cardiovascular Agent

What works? Research summarized

Evidence reviews

Calcium channel blockers for pulmonary arterial hypertension

The blood pressure in the arteries of the lungs is normally much lower than the blood pressure in the rest of the body. Pulmonary hypertension occurs when the pulmonary arterial pressure gradually rises which causes damage to the heart, and can finally lead to heart failure and death. Calcium channel blockers are drugs which can relax the pulmonary arteries and decrease resistance and pressure of these vessels; this may benefit patients with pulmonary hypertension.

Calcium antagonists as an add‐on therapy for drug‐resistant epilepsy

There is no evidence to suggest that calcium antagonists have a useful effect on seizures.

Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour

Calcium channel blockers have not been shown to reduce preterm birth or improve the outcomes for babies when given to women after contractions of preterm labour have been stopped.

See all (89)

Summaries for consumers

Calcium channel blockers for pulmonary arterial hypertension

The blood pressure in the arteries of the lungs is normally much lower than the blood pressure in the rest of the body. Pulmonary hypertension occurs when the pulmonary arterial pressure gradually rises which causes damage to the heart, and can finally lead to heart failure and death. Calcium channel blockers are drugs which can relax the pulmonary arteries and decrease resistance and pressure of these vessels; this may benefit patients with pulmonary hypertension.

Calcium antagonists as an add‐on therapy for drug‐resistant epilepsy

There is no evidence to suggest that calcium antagonists have a useful effect on seizures.

Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour

Calcium channel blockers have not been shown to reduce preterm birth or improve the outcomes for babies when given to women after contractions of preterm labour have been stopped.

See all (17)

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