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Mechlorethamine (By injection)

Treats Hodgkin's disease and other kinds of lymphoma and leukemia.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Mechlorethamine belongs to the group of medicines called alkylating agents. It is used to treat some kinds of cancer as well as some noncancerous conditions. Mechlorethamine interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by mechlorethamine, other effects will also occur. Some of these may be serious and must be… Read more
Brand names include
Mustargen
Other forms
On the skin
Drug classes About this
Antineoplastic Agent

What works? Research summarized

Evidence reviews

Effect of initial treatment strategy on survival of patients with advanced-stage Hodgkin's lymphoma: a systematic review and network meta-analysis

BACKGROUND: Several treatment strategies are available for adults with advanced-stage Hodgkin's lymphoma, but studies assessing two alternative standards of care-increased dose bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPPescalated), and doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD)-were not powered to test differences in overall survival. To guide treatment decisions in this population of patients, we did a systematic review and network meta-analysis to identify the best initial treatment strategy.

Summaries for consumers

Late Effects of Treatment for Childhood Cancer (PDQ®): Patient Version

Expert-reviewed information summary about the health problems that continue or appear after cancer treatment has ended.

PubMed Health Blog...

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