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Ixabepilone (By injection)

Treats advanced breast cancer. Used alone or with another cancer medicine called capecitabine.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Ixabepilone injection belongs to the group of medicines called antineoplastics (cancer medicines). It is used to treat advanced or metastatic breast cancer (breast cancer that has already spread) after other treatments have failed. Ixabepilone is given alone or with another cancer medicine called capecitabine. Ixabepilone interferes with the growth of cancer cells, which are eventually destroyed.… Read more
Brand names include
Ixempra
Drug classes About this
Antineoplastic Agent

What works? Research summarized

Evidence reviews

Ixabepilone plus capecitabine with capecitabine alone for metastatic breast cancer

The authors concluded that compared with capecitabine alone, ixabepilone plus capecitabine demonstrated a clinical activity with an acceptable safety profile in patients with locally-advanced breast cancer. There were concerns with trial quality and comparability, so caution is warranted when interpreting the authors’ conclusions.

Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data

BACKGROUND: Estramustine phosphate is a mustard-oestradiol conjugate, and has hormonal and non-hormonal effects. In phase II trials of patients with cancer, response to microtubule inhibitors increases when these drugs are combined with estramustine. We aimed to assess whether combining estramustine with chemotherapy increases survival in patients with castration-refractory prostate cancer.

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