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Hydrocortisone/Pramoxine (Into the rectum)

Treats inflammation of the rectum and anus. This medicine contains a corticosteroid.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Brand names include
Proctofoam-HC, Zypram
Other forms
On the skin
Drug classes About this
Hemorrhoidal, Anesthetic/Anti-Inflammatory Combination

What works? Research summarized

Evidence reviews

Local cooling for relieving pain from perineal trauma sustained during childbirth

Perineal tears are common during the birth of a baby. In addition, sometimes the caregiver will cut the perineum to give extra space for the baby to be born (episiotomy). These tears and cuts often cause pain for women in the hours, days and sometimes months after the birth. This can reduce a woman's ability to walk and to sit comfortably, and it may affect her ability to care for her baby, including breastfeeding. Women often use a number of methods to relieve the pain, including cold baths, ice or cold packs on the area. It is important to know if cooling works, and that, even though it is unlikely to occur in this region of the body, too much cooling may possibly delay healing or cause ice burns.

Postnatal Care: Routine Postnatal Care of Women and Their Babies [Internet]

This guideline has been written within a conceptual framework which places the woman and her baby at the centre of care, appreciating that all postnatal care should be delivered in partnership with the woman and should be individualised to meet the needs of each mother-infant dyad. The guideline aims to identify the essential ‘core care’ which every woman and her baby should receive, as appropriate to their needs, during the first 6–8 weeks after birth, based upon the best evidence available.

Summaries for consumers

Local cooling for relieving pain from perineal trauma sustained during childbirth

Perineal tears are common during the birth of a baby. In addition, sometimes the caregiver will cut the perineum to give extra space for the baby to be born (episiotomy). These tears and cuts often cause pain for women in the hours, days and sometimes months after the birth. This can reduce a woman's ability to walk and to sit comfortably, and it may affect her ability to care for her baby, including breastfeeding. Women often use a number of methods to relieve the pain, including cold baths, ice or cold packs on the area. It is important to know if cooling works, and that, even though it is unlikely to occur in this region of the body, too much cooling may possibly delay healing or cause ice burns.

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