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Hydrocodone/Chlorpheniramine/Pseudoephedrine (By mouth)

Treats cough and stuff nose. This medicine contains a narcotic.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Hydrocodone, chlorpheniramine, and pseudoephedrine combination is used to relieve cough and nasal congestion associated with the common cold and upper respiratory allergies. Hydrocodone is a narcotic antitussive (cough suppressant). It acts directly on the cough center in the brain to relieve cough. Chlorpheniramine is an antihistamine, which is used to relieve or prevent symptoms of an allergy. Read more
Brand names include
Hydron PSC, Hyphed, Notuss-Forte, Vasofrinic Dh, Zutripro
Drug classes About this
Antitussive, Opioid/Antihistamine/Decongestant Combination

What works? Research summarized

Evidence reviews

Assessment and Management of Chronic Cough [Internet]

Cough is the most common complaint for patients seeking medical attention in the United States. Although the most common cause of cough is acute self-limited viral infections, chronic cough (cough that lasts more than 4 weeks in children <14 years of age or more than 8 weeks in adolescents and adults) has a significant impact on quality of life and is responsible for up to 38 percent of pulmonary outpatient visits. Furthermore, a treatable cause is absent in up to 46 percent of patients with chronic cough despite a thorough diagnostic investigation. The comparative value of tools for assessing cough and the comparative effectiveness of treatments for unexplained or refractory cough are uncertain.

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