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Hydrocodone/Acetaminophen (By mouth)

Treats pain. This medicine contains a narcotic pain reliever.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Hydrocodone and acetaminophen combination is used to relieve moderate to moderately severe pain. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage. Hydrocodone belongs to the group of medicines called narcotic analgesics… Read more
Brand names include
Anexsia, Ceta Plus, Co-Gesic, Dolorex Forte, Hycet, Lorcet, Lorcet HD, Lorcet Plus, Lortab, Lortab 10/325, Lortab 5/325, Lortab 7.5/325, Lortab Elixir, Maxidone, Norco, Stagesic, Verdrocet, Vicodin, Vicodin ES, Vicodin HP, Xodol, Xodol 5/300, Zydone
Drug classes About this
Analgesic, Opioid/Acetaminophen Combination

What works? Research summarized

Evidence reviews

Noninvasive Treatments for Low Back Pain [Internet]

Low back pain is common, and many pharmacological and nonpharmacological therapies are available. This review examines the evidence on the comparative benefits and harms of noninvasive treatments for low back pain.

Drug Class Review: Drugs for Fibromyalgia: Final Original Report [Internet]

We compared the effectiveness and harms of tricyclic antidepressants, serotonin norepinephrine reuptake inhibitors, selective serotonin reuptake inhibitors, selective serotonin and norepinephrine reuptake inhibitors, noradrenergic and specific serotonergic reuptake inhibitor, norepinephrine and dopamine reuptake inhibitor, serotonin receptor antagonist, antiepileptic drugs, and skeletal muscle relaxants in adults with fibromyalgia.

Drug Class Review: Newer Antiemetics: Final Report Update 1 [Internet]

Nausea and vomiting are major concerns for patients undergoing chemotherapy, radiation therapy and surgery with general anesthesia. Risk factors associated with chemotherapy-induced nausea and vomiting include emetogenicity of the chemotherapy regimen, dose, speed of intravenous infusion, female gender, age under 50 years, history of ethanol consumption, and history of prior chemotherapy. Factors predictive of radiation therapy-induced nausea and vomiting include site of irradiation (in particular, total body irradiation and radiation fields that include the abdomen), total field size, dose per fraction, age, and predisposition for emesis (history of sickness during pregnancy or motion sickness). Female gender, a history of motion sickness or prior postoperative nausea and vomiting, nonsmoking status, and use of postoperative opioids have been suggested as factors predictive of postoperative nausea and vomiting. The objective of this review was to evaluate the comparative effectiveness and harms of newer antiemetic drugs including the 5-HT3 and NK-1 antagonists.

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Summaries for consumers

Noninvasive Treatments for Low Back Pain: A Summary of the Research for Adults

This summary will answer these questions: What is low back pain? How is low back pain treated? » Medicines » Nonmedicine treatments such as heat, exercise, and massage What have researchers found about treatments for low back pain? What are possible side effects of medicines to treat low back pain? What should I discuss with my health care professional about treating my low back pain?

Cancer Pain (PDQ®): Patient Version

Expert-reviewed information summary about pain as a complication of cancer or its treatment. Approaches to the management and treatment of cancer-associated pain are discussed.

PubMed Health Blog...

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