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Folic Acid/Cyanocobalamin (Vitamin B12)/Pyridoxine (Vitamin B6) (By mouth)

Raises levels of folic acid, vitamin B6, and vitamin B12 in your blood, which could help lower the amount of homocysteine (an amino acid) in your blood. Too much homocysteine may lead to heart and blood vessel problems. This medicine is a combination of vitamins.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Brand names include
Av-Vite FB, Av-Vite FB Forte, Carlson Homocysteine Guard, FaBB, Folbee, Folbic, Folgard RX, Folplex 2.2, Foltabs 800, Lev-Tov, Nature's Blend B Complex + Folic Acid, Niva-Fol, TL Gard Rx, Tri-B, Virt-Gard
Drug classes About this
Vitamin B Combination

What works? Research summarized

Evidence reviews

Folic Acid Supplementation: An Evidence Review for the U.S. Preventive Services Task Force [Internet]

To assess the benefits and harms of folic acid supplementation in reproductive-age women for the prevention of neural tube defects (NTDs).

Vitamin, Mineral, and Multivitamin Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: A Systematic Evidence Review for the U.S. Preventive Services Task Force [Internet]

In the United States, dietary supplements are commonly used to prevent chronic diseases, including cardiovascular disease (CVD) and cancer.

B vitamins and berries and age-related neurodegenerative disorders

This review found insufficient evidence to assess the effects of B vitamin supplementation on cognitive function. The authors' conclusions appear appropriately cautious in view of the poor methodological quality and small sample sizes of many of the included studies.

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Summaries for consumers

Homocysteine‐lowering interventions (B‐complex vitamin therapy) for preventing cardiovascular events

We reviewed homocysteine‐lowering interventions for preventing cardiovascular events.

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