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Febuxostat (By mouth)

Used to treat hyperuricemia (high uric acid in the blood) in patients with gout. This medicine is a xanthine oxidase inhibitor.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Febuxostat is used to treat hyperuricemia (high uric acid in the blood) in patients with gout. This medicine is a xanthine oxidase inhibitor. It works by causing less uric acid to be produced by the body. This medicine is available only with your doctor's prescription… Read more
Brand names include
Uloric
Drug classes About this
Antigout

What works? Research summarized

Evidence reviews

Febuxostat for treating chronic gout

This summary of a Cochrane review represents what we know from research about the effect of febuxostat for treating chronic gout.

A systematic review and meta-analysis on the safety and efficacy of febuxostat versus allopurinol in chronic gout

OBJECTIVE: To evaluate the safety and efficacy of febuxostat compared to allopurinol for the treatment of chronic gout.

Efficacy and tolerability of febuxostat in hyperuricemic patients with or without gout: a systematic review and meta-analysis

BACKGROUND: Febuxostat has been approved for the treatment of hyperuricemia in patients with/without gout.

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Summaries for consumers

Febuxostat for treating chronic gout

This summary of a Cochrane review represents what we know from research about the effect of febuxostat for treating chronic gout.

Allopurinol for chronic gout

This summary of a Cochrane review presents what we know from research about the effect of allopurinol compared with placebo or other treatments that reduce uric acid levels in treating people with chronic gout. The review is current to January 2014.

Preventing gout with medication

Gout cannot always be controlled just by changing diet or drinking less alcohol. Medication to lower uric acid levels may then be an option. It is a particularly good idea if there is a risk of gout becoming chronic or causing complications.Gout is caused by high uric acid levels. If uric acid levels in the blood are too high, urate crystals can start to form in the joints and cause acute gout attacks. Left untreated, gout can become chronic and do lasting damage to the joints. Keeping uric acid levels as low as possible is the most common approach when trying to prevent gout attacks and complications. Some people just have to change their diet and avoid other possible triggers, but others need to take medication to lower their uric acid levels over the long term.

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