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Ethosuximide (By mouth)

Treats seizures in patients who have epilepsy.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Ethosuximide is used to control absence (petit mal) seizures in the treatment of epilepsy. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. This medicine is available only with your doctor's prescription… Read more
Brand names include
Zarontin
Drug classes About this
Anticonvulsant

What works? Research summarized

Evidence reviews

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents

Epilepsy is a disorder where seizures are caused by abnormal electrical discharges from the brain. Absence epilepsy involves seizures that cause a sudden loss of awareness. It often starts in childhood or adolescence. Three antiepileptic drugs are often used for absence epilepsy: valproate, ethosuximide and lamotrigine.

The Epilepsies: The Diagnosis and Management of the Epilepsies in Adults and Children in Primary and Secondary Care: Pharmacological Update of Clinical Guideline 20

This guideline is a partial update of ‘The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care’ (NICE clinical guideline 20, 2004). It updates the pharmacological management sections of the 2004 guideline and also includes the use of the ketogenic diet.

Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy [Internet]

This is an evidence report prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice Center examining the comparative efficacy, safety, and tolerability of newer versus older and innovator versus generic antiepileptic medications.

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Summaries for consumers

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents

Epilepsy is a disorder where seizures are caused by abnormal electrical discharges from the brain. Absence epilepsy involves seizures that cause a sudden loss of awareness. It often starts in childhood or adolescence. Three antiepileptic drugs are often used for absence epilepsy: valproate, ethosuximide and lamotrigine.

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