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Ethacrynate Sodium (By injection)

Quickly lowers the amount of fluid in your body.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Ethacrynate sodium injection belongs to a group of medicines called loop diuretics or "water pills." Ethacrynate sodium is given to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions. It works by acting on the kidneys to increase the flow of urine . This medicine is available only with your… Read more
Brand names include
Edecrin Sodium, Ethacrynate Sodium Novaplus, PremierPro Rx Ethacrynate Sodium, Sodium Edecrin
Drug classes About this
Cardiovascular Agent

What works? Research summarized

Evidence reviews

Loop diuretics for patients receiving blood transfusions

Blood transfusions are often complicated by water retention, which may worsen lung function, heart function and/or kidney function. Loop diuretics, medications that reduce body water by making the kidneys excrete more urine, are thought to prevent water retention. Accordingly, many doctors pre‐medicate their blood transfusion recipients with loop diuretics.

Acute Heart Failure: Diagnosing and Managing Acute Heart Failure in Adults

The need for this guideline was identified as the NICE guidelines on chronic heart failure were being updated. We recognised at this time that there were important aspects of the diagnosis and management of acute heart failure that were not being addressed by the chronic heart failure guideline, which focussed on long term management rather than the immediate care of someone who is acutely unwell as a result of heart failure. The aim of this guideline is to provide guidance to the NHS on the diagnosis and management of acute heart failure.

Nebulized furosemide for the management of dyspnea: does the evidence support its use?

The authors concluded that nebulized furosemide appeared to have a positive effect on dyspnoea and physiological measurements, but the conclusions were limited by the small scale or methodological limitations of many included studies. Given the unclear quality of the included studies, the reliability of the authors' conclusions is unclear and their caution is justified.

Summaries for consumers

Loop diuretics for patients receiving blood transfusions

Blood transfusions are often complicated by water retention, which may worsen lung function, heart function and/or kidney function. Loop diuretics, medications that reduce body water by making the kidneys excrete more urine, are thought to prevent water retention. Accordingly, many doctors pre‐medicate their blood transfusion recipients with loop diuretics.

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