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Diphtheria/Tetanus/Acellular Pertussis/Polio Vaccine (By injection)

Protects against infections caused by diphtheria, tetanus (lockjaw), pertussis (whooping cough), and polio.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Diphtheria, tetanus, and acellular pertussis vaccine (also known as DTaP) combined with inactivated poliovirus vaccine (also known as IPV) is a combination vaccine that is given to protect against infections caused by diphtheria, tetanus (lockjaw), pertussis (whooping cough), and poliovirus. The vaccine works by causing the body to produce its own protection (antibodies) against these diseases.… Read more
Brand names include
Kinrix, Pentacel, Quadracel
Drug classes About this
Vaccine
Combinations including this drug

What works? Research summarized

Evidence reviews

Combined DTP‐HBV‐HIB vaccine versus separately administered DTP‐HBV and HIB vaccines in healthy infants up to two years old

Childhood vaccinations provide an effective method of protection against diseases. The World Health Organization (WHO) recommends that routine infant immunisation programmes include a vaccination against Haemophilus influenzae (H. influenza) type B (HIB) in the combined diphtheria‐tetanus‐pertussis (DTP)‐hepatitis B virus (HBV) vaccination. We compared the combined DTP‐HBV‐HIB vaccine with the separate DTP‐HBV and HIB vaccines. Studies only reported on immunogenicity and reactogenicity.

Safety of Vaccines Used for Routine Immunization in the United States

To conduct a systematic review of the literature on the safety of vaccines recommended for routine immunization of children, adolescents, and adults in the United States as of 2011.

Outreach programmes for health improvement of Traveller Communities: a synthesis of evidence

The study found no evidence to suggest the requirement to develop Traveller-specific health services. Outreach can be used to develop the cultural sensitivity, accessibility and acceptability of mainstream services. Texting appointment reminders is unlikely to be expensive and might constitute the minimum acceptable action to facilitate access to health care. Appropriate payment for the registration of Traveller Community members by general practitioners might also improve access. Mobile clinics are associated with the highest costs reported, with little indication of their acceptability or cost-effectiveness. Evidence suggests that outreach is likely to be more effective when delivered by workers who share the recipients’ ethnicity.

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Summaries for consumers

Combined DTP‐HBV‐HIB vaccine versus separately administered DTP‐HBV and HIB vaccines in healthy infants up to two years old

Childhood vaccinations provide an effective method of protection against diseases. The World Health Organization (WHO) recommends that routine infant immunisation programmes include a vaccination against Haemophilus influenzae (H. influenza) type B (HIB) in the combined diphtheria‐tetanus‐pertussis (DTP)‐hepatitis B virus (HBV) vaccination. We compared the combined DTP‐HBV‐HIB vaccine with the separate DTP‐HBV and HIB vaccines. Studies only reported on immunogenicity and reactogenicity.

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