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Clarithromycin (By mouth)

Treats and prevents infections. Also treats duodenal ulcers caused by H pylori. This medicine is a macrolide antibiotic.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection. Clarithromycin belongs to the class of medicines, known as macrolide antibiotics. It works by killing bacteria or… Read more
Brand names include
Biaxin, Biaxin Filmtab, Biaxin XL, Omeclamox-Pak, Prevpac, Triple Therapy
Drug classes About this
Antibiotic
Combinations including this drug

What works? Research summarized

Evidence reviews

Clarithromycin extended-release and immediate-release formulations in the treatment of patients with acute exacerbation of chronic bronchitis: a systematic review

Bibliographic details: Huang BL, Hu SL, Shen G, Wu L, Xu TJ, Chen Y, Xu WP.  Clarithromycin extended-release and immediate-release formulations in the treatment of patients with acute exacerbation of chronic bronchitis: a systematic review. Chinese Journal of Evidence-Based Medicine 2011; 11(6): 693-697 Available from: http://www.cjebm.org.cn/oa/DArticle.aspx?type=view&id=201106017

Antibiotics to treat adults with acute laryngitis

Cochrane authors reviewed the available evidence from randomised controlled trials on the use of antibiotics for adults with acute laryngitis.

Anti‐tuberculous therapy for maintaining remission in Crohn's disease

Tuberculous bacteria have been suggested as a possible cause of Crohn's disease due to a similarity between Crohn's and tuberculous lesions when viewed under a microscope. Four studies examined the use of anti‐tuberculous therapy to reduce the chance of the disease recurring in patients with non‐active Crohn's disease. The results of these studies suggest that this treatment might be effective for this purpose. However, this finding has not been definitively proven, and anti‐tuberculous therapy should not be used to treat Crohn's disease without further study.

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Summaries for consumers

Antibiotics to treat adults with acute laryngitis

Cochrane authors reviewed the available evidence from randomised controlled trials on the use of antibiotics for adults with acute laryngitis.

Anti‐tuberculous therapy for maintaining remission in Crohn's disease

Tuberculous bacteria have been suggested as a possible cause of Crohn's disease due to a similarity between Crohn's and tuberculous lesions when viewed under a microscope. Four studies examined the use of anti‐tuberculous therapy to reduce the chance of the disease recurring in patients with non‐active Crohn's disease. The results of these studies suggest that this treatment might be effective for this purpose. However, this finding has not been definitively proven, and anti‐tuberculous therapy should not be used to treat Crohn's disease without further study.

Ideal length of treatment for Helicobacter pylori (H. pylori) eradication

The ideal duration of therapy for H. pylori eradication is controversial, with recommendations ranging from 7 to 14 days. A proton pump inhibitor (PPI) plus two antibiotics is the most commonly used first treatment to remove H. pylori infection. Current data suggest that increasing the length of treatment to 14 days of a PPI plus amoxicillin and clarithromycin or amoxicillin and a nitroimidazole significantly increases the eradication rate, while increasing the adverse events by a small amount. Based on the overall evidence, the ideal length of treatment with a PPI plus amoxicillin and clarithromycin is at least 14 days.

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