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Citrate (Oral route)

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Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Citrates are used to make the urine more alkaline (less acid). This helps prevent certain kinds of kidney stones. Citrates are sometimes used with other medicines to help treat kidney stones that may occur with gout. They are also used to make the blood more alkaline in certain conditions Citrates are available only with your doctor's prescription… Read more
Brand names include
Citra pH, Cytra-K, Cytra-K Crystals, Liqui-DualCitra, Pms-Dicitrate, Polycitra-K, Polycitra-K Crystals, Urocit-K 10, Urocit-K 15, Urocit-K 5

What works? Research summarized

Evidence reviews

Long versus short course treatment with Metformin + Clomiphene Citrate for ovulation induction in women with PCOS

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among women of reproductive‐age. Apart from infertility, women with PCOS often have other endocrine disorders, including insulin resistance, hyperinsulinaemia and hyperandrogenism. Metformin combined with clomiphene citrate (CC), has been shown to be more effective in ovulation induction than clomiphene citrate alone. The optimal duration for metformin pretreatment before initiation of clomiphene citrate, however, is unknown. There have been no trials conducted to determine the effectiveness of short‐course (less than four weeks) metformin plus clomiphene citrate compared to the conventional long‐course (four weeks or more) metformin plus clomiphene citrate with regard to ovulation and achievement of pregnancy in infertile women with polycystic ovary syndrome.

Clomiphene citrate for unexplained subfertility in women

Clomiphene citrate is a fertility drug that can increase the number of eggs released for possible fertilisation. It is used by women who do not ovulate regularly and by some who do but still have not become pregnant. Clomiphene citrate does not appear to increase the chance of pregnancy in women who ovulate regularly but have failed to conceive after more than a year of unprotected intercourse and so are considered to be subfertile. An associated risk of treatment with clomiphene citrate is a 10% chance of multiple pregnancy. The results of this review of trials should be used with caution due to the heterogeneity between some of the studies.

Treatments with Viagra (Sildenafil citrate)  for erectile dysfunction in male patients aged more than 18 years old with multiple sclerosis

Erectile dysfunction (ED) is a common sexual disease in male patients with multiple sclerosis (MS). Viagra (Sildenafil citrate) is considered as an effective drug for  the treatment of ED in the general population, but it has not been systematically reviewed in patients with MS.

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Summaries for consumers

Long versus short course treatment with Metformin + Clomiphene Citrate for ovulation induction in women with PCOS

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among women of reproductive‐age. Apart from infertility, women with PCOS often have other endocrine disorders, including insulin resistance, hyperinsulinaemia and hyperandrogenism. Metformin combined with clomiphene citrate (CC), has been shown to be more effective in ovulation induction than clomiphene citrate alone. The optimal duration for metformin pretreatment before initiation of clomiphene citrate, however, is unknown. There have been no trials conducted to determine the effectiveness of short‐course (less than four weeks) metformin plus clomiphene citrate compared to the conventional long‐course (four weeks or more) metformin plus clomiphene citrate with regard to ovulation and achievement of pregnancy in infertile women with polycystic ovary syndrome.

Clomiphene citrate for unexplained subfertility in women

Clomiphene citrate is a fertility drug that can increase the number of eggs released for possible fertilisation. It is used by women who do not ovulate regularly and by some who do but still have not become pregnant. Clomiphene citrate does not appear to increase the chance of pregnancy in women who ovulate regularly but have failed to conceive after more than a year of unprotected intercourse and so are considered to be subfertile. An associated risk of treatment with clomiphene citrate is a 10% chance of multiple pregnancy. The results of this review of trials should be used with caution due to the heterogeneity between some of the studies.

Treatments with Viagra (Sildenafil citrate)  for erectile dysfunction in male patients aged more than 18 years old with multiple sclerosis

Erectile dysfunction (ED) is a common sexual disease in male patients with multiple sclerosis (MS). Viagra (Sildenafil citrate) is considered as an effective drug for  the treatment of ED in the general population, but it has not been systematically reviewed in patients with MS.

See all (27)

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