Home > Drugs A – Z > Bisoprolol (By mouth)

Bisoprolol (By mouth)

Treats high blood pressure. This medicine is a beta blocker.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Bisoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure… Read more
Brand names include
Drug classes About this
Antianginal, Antihypertensive, Cardiovascular Agent
Combinations including this drug

What works? Research summarized

Evidence reviews

Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol).

Because carvedilol is a unique vasodilating β blocker (BB) exerting antioxidant activity and pleiotropic effects, it was theorized that it may confer more potent beneficial effects on cardiovascular mortality and morbidity in acute myocardial infarction (AMI) and heart failure (HF) settings. A systematic review and meta-analysis was performed of randomized, controlled, direct-comparison trials that included adults receiving atenolol, bisoprolol, metoprolol, nebivolol, or carvedilol to evaluate the effects of carvedilol compared to other BBs on mortality, cardiovascular events, and hospital readmissions in the setting of AMI or systolic HF. Compared to β(1)-selective BBs used in HF (8 trials, n = 4,563), carvedilol significantly reduced all-cause mortality (risk ratio 0.85, 95% confidence interval 0.78 to 0.93, p = 0.0006). In 3 trials of patients with AMI (n = 644), carvedilol significantly reduced all-cause mortality by 45% (fixed-effects model: risk ratio 0.55, 95% confidence interval 0.32 to 0.94, p = 0.03, random-effects model: risk ratio 0.56, 95% confidence interval 0.26 to 1.12, p = 0.10), with no reduction in non-fatal MI (risk ratio 0.61, 95% confidence interval 0.31 to 1.22, p = 0.16). In conclusion, carvedilol, as compared against atenolol, bisoprolol, metoprolol and nebivolol in randomized direct comparison trials, significantly reduced all-cause mortality in systolic HF patients. Additionally, carvedilol significantly reduced all-cause mortality compared with β(1)-selective BBs in AMI patients using the fixed-effects model but not using the random-effects model.

Effects of beta-blockers for congestive heart failure in pediatric and congenital heart disease patients: a meta-analysis of published studies

BACKGROUND AND AIM: The effects of beta--blockers in pediatric and congenital heart disease (CHD) patients suffering from heart failure are controversial. We performed a meta--analysis to determine whether beta--blockers are effective for heart failure in pediatric and CHD patients.

Further data on beta-blockers and cancer risk: Observational study and meta-analysis of randomized clinical trials.

BACKGROUND: The aim of the present paper is to provide some further data on the relationship between β-blocker treatment and the incidence of cancer, using two different approaches (epidemiological study and meta-analysis of clinical trials).

See all (46)

Summaries for consumers

Comparing Beta Blockers

How do beta blockers compare in hypertension?

Medication for the long-term treatment of coronary artery disease

The long-term treatment of coronary artery disease (CAD) mainly involves taking medication. Various medications can relieve the symptoms and lower the risk of complications.In order to prevent the development of related medical conditions, all people who have coronary artery disease (CAD) are advised to take two types of medication: Antiplatelets to prevent blood clots, and statins to protect the blood vessels.Beta blockers are sometimes taken too, to reduce the heart's workload, particularly in people who have heart failure or high blood pressure.Good-quality studies have proven that these medications can lower the risk of complications such as heart attacks or strokes. People who have certain other medical conditions too may take other medications such as ACE inhibitors. But even the very best treatment with medications will offer only limited protection from heart disease.All medications can have side effects. Yet it is often possible to avoid them by adjusting the dose or by choosing a different medication in the same group of drugs. The side effects often go away after a while too, once the body has got used to the medication.The risk of side effects may increase when two or more medications are taken together, because they may interact. It is therefore important to tell your doctor what medication you are already taking.Generally speaking, the more risk factors someone has, the more likely it is that he or she will benefit from medication. The important thing is to continue to take your medication and to take it regularly – its protective effect lasts only as long as it is taken.

Beta‐1 selective blockers for treatment of high blood pressure

Beta‐1 selective blockers are a subclass of beta blockers that are commonly used to treat high blood pressure. Drugs in this class include atenolol (Tenormin), metoprolol (Lopressor), nebivolol (Bystolic) and bisoprolol (Zebeta, Monocor). We developed a comprehensive methodology to examine how different doses and drugs in this class of drugs lower blood pressure.

See all (4)

PubMed Health Blog...

read all...