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Benzonatate (By mouth)

Treats cough.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Benzonatate is used to relieve coughs due to colds or influenza (flu). It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. It may also act on the cough center in the brain. This medicine is available… Read more
Brand names include
Tessalon Perles, Zonatuss
Drug classes About this
Antitussive

What works? Research summarized

Evidence reviews

Assessment and Management of Chronic Cough [Internet]

Cough is the most common complaint for patients seeking medical attention in the United States. Although the most common cause of cough is acute self-limited viral infections, chronic cough (cough that lasts more than 4 weeks in children <14 years of age or more than 8 weeks in adolescents and adults) has a significant impact on quality of life and is responsible for up to 38 percent of pulmonary outpatient visits. Furthermore, a treatable cause is absent in up to 46 percent of patients with chronic cough despite a thorough diagnostic investigation. The comparative value of tools for assessing cough and the comparative effectiveness of treatments for unexplained or refractory cough are uncertain.

The clinical effectiveness and cost-effectiveness of treatments for idiopathic pulmonary fibrosis: a systematic review and economic evaluation

The study found that few interventions for idiopathic pulmonary fibrosis have any statistically significant effect, and identified a lack of studies on palliative care approaches. Few direct comparisons of treatments were identified; an indirect comparison was performed through network meta-analysis, but the results should be interpreted with caution.

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