Home > Drugs A – Z > Ambrisentan (By mouth)

Ambrisentan (By mouth)

Treats pulmonary arterial hypertension.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Ambrisentan is used to treat symptoms of pulmonary arterial hypertension, which is high blood pressure in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the small blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Ambrisentan works by relaxing these… Read more
Brand names include
Letairis
Drug classes About this
Antihypertensive

What works? Research summarized

Evidence reviews

Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness [Internet]

The objective of this therapeutic review is to conduct a systematic review to assess the comparative efficacy and safety and to determine the cost-effectiveness of drug therapies for the treatment of pulmonary arterial hypertension (PAH) in adults.

Macitentan (Opsumit): For Long-Term Treatment of Pulmonary Arterial Hypertension [Internet]

Pulmonary arterial hypertension (PAH; also classified as Group 1 pulmonary hypertension [PH]) is a rare, debilitating, progressive, and life-threatening disease of the pulmonary vasculature, characterized by vascular proliferation and remodelling of small pulmonary arteries. PAH is defined by an increase in mean pulmonary arterial pressure (mPAP) ≥ 25 mm Hg and a pulmonary wedge pressure of ≤ 15 mm Hg. If left untreated, it can lead to right heart failure and premature death.

Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness — Recommendations Report [Internet]

The Canadian Drug Expert Committee (CDEC) recommends that sildenafil or tadalafil be the preferred initial therapy for adult patients with functional class (FC) II and III pulmonary arterial hypertension (PAH).

See all (13)

PubMed Health Blog...

read all...