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Triamcinolone

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

For the teeth or gums

Treats pain and redness caused by mouth sores or gum problems. Belongs to a class of drugs called corticosteroids… Read more

Brand names include: Oralone

By injection

Triamcinolone injection is used to treat inflammation (swelling), allergic reactions, certain types of arthritis, gout, skin diseases, and many other… Read more

Brand names include: Active Injection Kit KL-3, Active Injection Kit KM

Into the nose

Triamcinolone nasal spray is used to treat an itchy or runny nose, sneezing, or other symptoms caused by seasonal and perennial hay fever (allergic rhinitis)… Read more

Brand names include: Nasacort, Nasacort Allergy 24HR

On the skin

Triamcinolone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid… Read more

Brand names include: Aristocort A, Aristocort C Concentrate

Drug classes About this
Anti-Inflammatory, Corticosteroid, Intermediate, Dental Agent, Endocrine-Metabolic Agent, Immune Suppressant
Combinations including this drug

What works? Research summarized

Evidence reviews

Effectiveness and safety of laser photocoagulation plus intravitreal triamcinolone for diabetic macular edema: a meta-analysis

Bibliographic details: Xu CQ, Ma LJ.  Effectiveness and safety of laser photocoagulation plus intravitreal triamcinolone for diabetic macular edema: a meta-analysis. Chinese Journal of Evidence-Based Medicine 2012; 12(7): 817-821 Available from: http://www.cjebm.org.cn/oa/DArticle.aspx?type=view&id=2012070014

Clinical course and management of iatrogenic Cushing's syndrome after co-administration of injected-triamcinolone and ritonavir: a systematic review

Bibliographic details: John G, Ollo D, Meyer P, Herold M, Samer CF, Calmy A.  Clinical course and management of iatrogenic Cushing's syndrome after co-administration of injected-triamcinolone and ritonavir: a systematic review. Journal of Antivirals and Antiretrovirals 2013; 5(7): 180-184 Available from: http://omicsonline.org/clinical-course-and-management-of-iatrogenic-cushing-syndrome-jaa.1000086.php?aid=22049

Steroids with antiangiogenic properties for treating neovascular age‐related macular degeneration

Neovascular age‐related macular degeneration (AMD) is associated with rapid loss of vision due to abnormal growth of blood vessels in the macula. Corticosteroids that reduce this growth of blood vessels have been tested for treatment of such vision loss. This review included three trials evaluating two different types of steroids, triamcinolone acetonide and anecortave acetate, for the treatment of neovascular AMD. The findings across the three trials, which included a total of 809 participants, were consistent with no evidence of benefit, in terms of preventing vision loss, with antiangiogenic steroids compared with placebo or photodynamic therapy. Based on available evidence, there is little benefit of steroids with anti‐angiogenic properties in the treatment of neovascular age‐related macular degeneration.".

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Summaries for consumers

Steroids with antiangiogenic properties for treating neovascular age‐related macular degeneration

Neovascular age‐related macular degeneration (AMD) is associated with rapid loss of vision due to abnormal growth of blood vessels in the macula. Corticosteroids that reduce this growth of blood vessels have been tested for treatment of such vision loss. This review included three trials evaluating two different types of steroids, triamcinolone acetonide and anecortave acetate, for the treatment of neovascular AMD. The findings across the three trials, which included a total of 809 participants, were consistent with no evidence of benefit, in terms of preventing vision loss, with antiangiogenic steroids compared with placebo or photodynamic therapy. Based on available evidence, there is little benefit of steroids with anti‐angiogenic properties in the treatment of neovascular age‐related macular degeneration.".

Systemic corticosteroids for acute gout

‐ there is no precise information about side effects and complications. Only a minority of the patients treated with the steroid oral prednisolone reported minor side effects.

Intravitreal steroids for macular edema in people with diabetes

Macular edema, swelling of the center of the retina (the part of the eye responsible for our sharpest vision), is an important cause of poor vision in patients with diabetes. New forms of therapy are desirable because the current treatment including laser photocoagulation does not control all cases of diabetic macular edema (DME) and because laser therapy may destroy normal retinal tissue. Intraocular steroids in the form of intravitreal triamcinolone acetate injection (IVTA) and surgical implantation of fluocinolone acetonide (FAI) or dexamethasone drug delivery system (DDS) are promising new therapies. This systematic review included seven randomized clinical trials involving 632 eyes from five countries evaluating the effectiveness and safety of intravitreal steroids for treating DME. Two trials were at low risk of bias, one was at median risk of bias, two were at high risk of bias, and the remaining two had an unclear risk of bias. In this systematic review, the preponderance of data suggest a beneficial effect from IVTA. The average improvement in visual acuity was 7.5 letters more (‐0.15 LogMAR; 95% CI ‐0.21 to ‐0.09) in the IVTA treated eyes than in those treated with other therapies at three months (based on three trials), 11.5 letters more (‐0.23 LogMAR; 95% CI ‐0.33 to ‐0.13) at six months (two trials), 14.5 letters more (‐0.29 LogMAR; 95% CI ‐0.47 to ‐0.11) at nine months (one trial), and 5.7 letters more (‐0.11 LogMAR; 95% CI ‐0.20 to ‐0.03) at 24 months (one trial). Improved clinical outcomes were also reported in FAI and dexamethasone DDS trials. Elevation of intraocular pressure and cataract progression occur in both IVTA and implants treated eyes but appear manageable.

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