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Testosterone

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Absorbed through the skin

Testosterone transdermal patch is used for the treatment of males whose bodies do not make enough natural testosterone, a condition called hypogonadism… Read more

Brand names include: Androderm, Androplex

Between cheek and gum

Testosterone is used for the treatment of men whose bodies do not make enough natural testosterone, a condition called hypogonadism. Testosterone is a… Read more

Brand names include: Striant

By injection

Treats low testosterone levels. Also treats breast cancer in women and delayed puberty in male teenagers… Read more

Brand names include: Aveed, Delatestryl

On the skin

Testosterone topical gel is used for the treatment of males whose bodies do not make enough natural testosterone, a condition called hypogonadism. Testosterone… Read more

Brand names include: Androgel, Axiron

Intramuscular route

Testosterone injection is used for the treatment of men whose bodies do not make enough natural testosterone, a condition called hypogonadism. Testosterone… Read more

Brand names include: Aveed, Delatestryl

Into the nose

Testosterone nasal gel is used for the treatment of men whose bodies do not make enough natural testosterone, a condition called hypogonadism. Testosterone… Read more

Brand names include: Natesto

Drug classes About this
Androgen, Endocrine-Metabolic Agent

What works? Research summarized

Evidence reviews

Testosterone for schizophrenia

About 1% of people suffer from schizophrenia, a serious mental illness found in all societies and cultures. Many treatments options are available to reduce the dramatic symptoms of this illness such as the false beliefs (delusions) and false or distorted perceptions (hallucinations). Other symptoms, such as emotional withdrawal and apathy are also often seen with schizophrenia and seem less responsive to treatment with antipsychotic drugs. In addition, some people continue to experience delusions and hallucinations despite adequate use of antipsychotic drugs and often supplementary treatments are used. These supplementary treatments include sex hormones such as estrogen and testosterone.

Testosterone for perimenopausal and postmenopausal women

There is good evidence that adding testosterone to hormone therapy (HT) has a beneficial effect on sexual function in postmenopausal women. However, the combined therapy is associated with a higher incidence of hair growth and acne and a reduction in high‐density lipoprotein (HDL) cholesterol. These adverse events may vary with different doses and routes of administration of testosterone. Adding testosterone to HT did not increase the number of women who stopped HT therapy.

Testosterone and oestrogen steroid sex hormones for lower limb atherosclerosis

Atherosclerosis of the arteries of the legs can become symptomatic as people age. People affected may experience discomfort and cramping pain in the legs that is triggered by exercise and relieved with rest, termed intermittent claudication. Some people with claudication go on to require reconstructive surgery and even amputation of a leg. Risk factors for peripheral arterial disease include cigarette smoking, high blood pressure, high cholesterol, low levels of high density lipoprotein (HDL) cholesterol and blood flow problems. The steroid sex hormones oestrogens and testosterone affect a number of these risk factors, particularly cholesterol and blood clotting, and may be helpful in peripheral vascular disease.

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Summaries for consumers

Testosterone for schizophrenia

About 1% of people suffer from schizophrenia, a serious mental illness found in all societies and cultures. Many treatments options are available to reduce the dramatic symptoms of this illness such as the false beliefs (delusions) and false or distorted perceptions (hallucinations). Other symptoms, such as emotional withdrawal and apathy are also often seen with schizophrenia and seem less responsive to treatment with antipsychotic drugs. In addition, some people continue to experience delusions and hallucinations despite adequate use of antipsychotic drugs and often supplementary treatments are used. These supplementary treatments include sex hormones such as estrogen and testosterone.

Testosterone for perimenopausal and postmenopausal women

There is good evidence that adding testosterone to hormone therapy (HT) has a beneficial effect on sexual function in postmenopausal women. However, the combined therapy is associated with a higher incidence of hair growth and acne and a reduction in high‐density lipoprotein (HDL) cholesterol. These adverse events may vary with different doses and routes of administration of testosterone. Adding testosterone to HT did not increase the number of women who stopped HT therapy.

Testosterone and oestrogen steroid sex hormones for lower limb atherosclerosis

Atherosclerosis of the arteries of the legs can become symptomatic as people age. People affected may experience discomfort and cramping pain in the legs that is triggered by exercise and relieved with rest, termed intermittent claudication. Some people with claudication go on to require reconstructive surgery and even amputation of a leg. Risk factors for peripheral arterial disease include cigarette smoking, high blood pressure, high cholesterol, low levels of high density lipoprotein (HDL) cholesterol and blood flow problems. The steroid sex hormones oestrogens and testosterone affect a number of these risk factors, particularly cholesterol and blood clotting, and may be helpful in peripheral vascular disease.

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