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Sodium Bicarbonate

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

By mouth

Treats heartburn, acid indigestion, and sour or upset stomach. This is an antacid… Read more

Oral route, Intravenous route, Subcutaneous route

Sodium bicarbonate , also known as baking soda, is used to relieve heartburn, sour stomach, or acid indigestion by neutralizing excess stomach acid. When… Read more

Brand names include: Brioschi, Neut

Drug classes About this
Antacid, Sodium Bicarbonate Containing, Antidote
Combinations including this drug

What works? Research summarized

Evidence reviews

Is sodium bicarbonate therapy helpful for people with acute kidney problems?

Acute kidney damage is a common problem that is often found in people who need treatment for problems not related to kidney health. Failing kidney health often causes more acid than normal in the blood (acidosis), which in itself is thought to cause harm.

Sodium bicarbonate infusion during resuscitation of infants at birth

Intravenous infusion of sodium bicarbonate to newborn babies during resuscitation in the delivery room at birth. At birth some babies who do not start breathing spontaneously have an abnormal amount of acid in their blood. To treat this, an alkaline drug, sodium bicarbonate, has often been given intravenously. Although this has been common practice for over thirty years, there is no good evidence that this is beneficial and may cause harm. We found only one high quality study of 55 babies that compared sodium bicarbonate treatment with no treatment. The study did not show any benefit of the use of this drug immediately after birth, nor any adverse effects.

Use of sodium bicarbonate to treat organophosphorus pesticide poisoning

Many people, particularly in developing countries, are poisoned by organophosphorus pesticides (OPs) used in agriculture or for killing insects in the home. Poisoning may be accidental or intentional. Even when the usual antidotes are given, 10 to 20% of those poisoned still die. Research in animals has suggested that use of sodium bicarbonate (baking soda) or similar chemicals which make the blood alkaline might save people poisoned by OPs.

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Summaries for consumers

Is sodium bicarbonate therapy helpful for people with acute kidney problems?

Acute kidney damage is a common problem that is often found in people who need treatment for problems not related to kidney health. Failing kidney health often causes more acid than normal in the blood (acidosis), which in itself is thought to cause harm.

Sodium bicarbonate infusion during resuscitation of infants at birth

Intravenous infusion of sodium bicarbonate to newborn babies during resuscitation in the delivery room at birth. At birth some babies who do not start breathing spontaneously have an abnormal amount of acid in their blood. To treat this, an alkaline drug, sodium bicarbonate, has often been given intravenously. Although this has been common practice for over thirty years, there is no good evidence that this is beneficial and may cause harm. We found only one high quality study of 55 babies that compared sodium bicarbonate treatment with no treatment. The study did not show any benefit of the use of this drug immediately after birth, nor any adverse effects.

Use of sodium bicarbonate to treat organophosphorus pesticide poisoning

Many people, particularly in developing countries, are poisoned by organophosphorus pesticides (OPs) used in agriculture or for killing insects in the home. Poisoning may be accidental or intentional. Even when the usual antidotes are given, 10 to 20% of those poisoned still die. Research in animals has suggested that use of sodium bicarbonate (baking soda) or similar chemicals which make the blood alkaline might save people poisoned by OPs.

See all (20)

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