Home > Drugs A – Z > Morphine

Morphine

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Epidural route

Morphine epidural injection is used to relieve pain following a major surgery. It is given right before a surgery or during a cesarean section delivery… Read more

Brand names include: DepoDur

By injection

Morphine injection is used to relieve moderate to severe pain. It may also be used before or during surgery with an anesthetic (medicine that puts you… Read more

Brand names include: Astramorph PF, Astramorph/PF

Oral route

Morphine is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Morphine acts on… Read more

Brand names include: Arymo ER, Kadian

By injection

Treats pain after surgery. This medicine is a narcotic analgesic… Read more

By mouth

Treats moderate to severe pain. This medicine is a narcotic pain reliever… Read more

By mouth

Treats moderate to severe pain. This medicine is a narcotic pain reliever… Read more

Brand names include: Arymo ER, Kadian

Drug classes About this
Analgesic, Anesthetic Adjunct, Central Nervous System Agent, Opioid
Combinations including this drug

What works? Research summarized

Evidence reviews

Nebulised morphine for severe interstitial lung disease

Nebulized morphine has been reported to have some beneficial effect on breathlessness and exercise limitation in terminally ill patients with chronic lung disease. Patients with end‐stage interstitial lung disease might also benefit from treatment of breathlessness with nebulized morphine. This review evaluates the effectiveness of using nebulized morphine for breathlessness reduction in patients with interstitial lung disease. Only one small randomised controlled trial was identified. This study concluded that low‐dose nebulized morphine is of no benefit in the management of exercise‐induced dyspnoea and exercise limitations in patients with interstitial lung disease. However, the patients included in this study were relatively mild, and definitive conclusions on the effect of nebulized morphine in the reduction of dyspnoea in end‐stage interstitial lung disease requires further work.

Use of slow‐release oral morphine for the treatment of people with opioid dependence

Opioid dependence is associated with public health and social problems. People injecting opioids are particularly at risk, not only because they become dependent faster than with other routes of administration but also because they are exposed to consequences such as an increased risk of overdose mortality, infective diseases and health issues. At least three‐quarters of global opiate users consume heroin.

Morphine injections for pain relief after knee arthroscopy

Knee arthroscopy is a surgical procedure on the knee. The surgery is minimally invasive, which means that only a small cut (incision) is needed. An examination, and sometimes treatment, of damage is performed using an arthroscope, which is inserted into the joint through the small incision. Knee arthroscopy is used to assess or treat many orthopaedic (musculoskeletal) conditions, and patients may have pain after surgery. Morphine injected directly into the knee (intra‐articular morphine) to relieve pain has been widely studied, but we do not know how well it works.

See all (405)

Summaries for consumers

Nebulised morphine for severe interstitial lung disease

Nebulized morphine has been reported to have some beneficial effect on breathlessness and exercise limitation in terminally ill patients with chronic lung disease. Patients with end‐stage interstitial lung disease might also benefit from treatment of breathlessness with nebulized morphine. This review evaluates the effectiveness of using nebulized morphine for breathlessness reduction in patients with interstitial lung disease. Only one small randomised controlled trial was identified. This study concluded that low‐dose nebulized morphine is of no benefit in the management of exercise‐induced dyspnoea and exercise limitations in patients with interstitial lung disease. However, the patients included in this study were relatively mild, and definitive conclusions on the effect of nebulized morphine in the reduction of dyspnoea in end‐stage interstitial lung disease requires further work.

Use of slow‐release oral morphine for the treatment of people with opioid dependence

Opioid dependence is associated with public health and social problems. People injecting opioids are particularly at risk, not only because they become dependent faster than with other routes of administration but also because they are exposed to consequences such as an increased risk of overdose mortality, infective diseases and health issues. At least three‐quarters of global opiate users consume heroin.

Morphine injections for pain relief after knee arthroscopy

Knee arthroscopy is a surgical procedure on the knee. The surgery is minimally invasive, which means that only a small cut (incision) is needed. An examination, and sometimes treatment, of damage is performed using an arthroscope, which is inserted into the joint through the small incision. Knee arthroscopy is used to assess or treat many orthopaedic (musculoskeletal) conditions, and patients may have pain after surgery. Morphine injected directly into the knee (intra‐articular morphine) to relieve pain has been widely studied, but we do not know how well it works.

See all (111)

PubMed Health Blog...

read all...