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Miconazole

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Between cheek and gum

Miconazole buccal treats fungus (yeast) infections in the mouth and throat (oral thrush). It belongs to the group of medicines called antifungals and… Read more

Brand names include: Oravig

On the skin

Miconazole belongs to the group of medicines called antifungals. Topical miconazole is used to treat some types of fungus infections. Some of these preparations… Read more

Brand names include: Aloe Vesta 2-N-1 Antifungal, Aloe Vesta Antifungal

Into the vagina

Treats vaginal yeast infections. This medicine is an antifungal… Read more

Brand names include: Equate Miconazole 1, Equate Miconazole 7

Drug classes About this
Antifungal
Combinations including this drug

What works? Research summarized

Evidence reviews

Miconazole versus miconazole plus living preparation of lactobacillus for vulvovaginal candidiasis: a systematic review

Bibliographic details: Cui L, Wang C, Fu J, Xie LX, Hu LN.  Miconazole versus miconazole plus living preparation of lactobacillus for vulvovaginal candidiasis: a systematic review. Chinese Journal of Evidence-Based Medicine 2010; 10(1): 89-93

Prophylactic oral/topical non‐absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants

Background: Fungi such as candida (the organism that causes thrush) can cause bloddstream and other severe infections in VLBW infants (birth weight less than 1500 grams). These infections are often difficult to diagnose and frequently cause death or disability. Therefore, it may be appropriate to attempt to prevent such infections by giving VLBW infants antifungal drugs as a routine part of their care. This review assessed specifically the effect of giving infants antifungal drugs that reduce skin and gut carriage of fungi to reduce the chances of a severe infection developing.

Prevention of fungal infections in patients with cancer with antifungal drugs

Cancer patients receiving chemotherapy or a bone marrow transplant are at risk of fungal infections. These can be life‐threatening, especially when they spread throughout the body. Those patients with low white cell counts (neutropenia) are particularly at risk. Antifungal drugs are often given as a routine preventive measure, or when people who are at risk have a fever. The review found that intravenous amphotericin B could reduce the number of deaths. Three of the drugs, amphotericin B, fluconazole and itraconazole, reduced fungal infections.

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Summaries for consumers

Prophylactic oral/topical non‐absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants

Background: Fungi such as candida (the organism that causes thrush) can cause bloddstream and other severe infections in VLBW infants (birth weight less than 1500 grams). These infections are often difficult to diagnose and frequently cause death or disability. Therefore, it may be appropriate to attempt to prevent such infections by giving VLBW infants antifungal drugs as a routine part of their care. This review assessed specifically the effect of giving infants antifungal drugs that reduce skin and gut carriage of fungi to reduce the chances of a severe infection developing.

Prevention of fungal infections in patients with cancer with antifungal drugs

Cancer patients receiving chemotherapy or a bone marrow transplant are at risk of fungal infections. These can be life‐threatening, especially when they spread throughout the body. Those patients with low white cell counts (neutropenia) are particularly at risk. Antifungal drugs are often given as a routine preventive measure, or when people who are at risk have a fever. The review found that intravenous amphotericin B could reduce the number of deaths. Three of the drugs, amphotericin B, fluconazole and itraconazole, reduced fungal infections.

How effective are athlete's foot treatments?

Athlete's foot is very common and usually does not cause any serious problems. But affected skin can crack, and be itchy and unattractive. The fungus can spread to the nails, and on rare occasions to other areas of skin. The infection can usually be treated effectively with creams, gels or sprays.Athlete's foot fungi grow particularly well in the areas between our toes. It is often moist and warm there, and the skin on our feet is also a good breeding ground for fungus. Topical treatment will usually clear up the infection within a few weeks. Tablets only have to be taken in exceptional cases.Good hygiene is also important so that other people do not become infected and to prevent the infection from returning. That includes regularly changing socks, towels and bedding and washing them at over 60 degrees Celsius.

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