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Estrogen

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Oral route, Parenteral route, Topical application route, Transdermal route

Estrogens are female hormones. They are produced by the body and are necessary for the normal sexual development of the female and for the regulation… Read more

Brand names include: Alora, Cenestin

Vaginal route

Estrogens are hormones produced by the body. Among other things, estrogens help develop and maintain female organs. When your body is in short supply… Read more

Brand names include: Estrace, Estragyn

Combinations including this drug

What works? Research summarized

Evidence reviews

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes

Diethylstilbestrol during pregnancy poses serious long‐term risks for those exposed in the womb and offers no known benefit for mothers and children.

Progestogens with or without oestrogen for irregular menstrual bleeding

Irregular bleeding associated with infrequent or no ovulation occurs most commonly in adolescents and in women approaching the menopause. It may also occur in those with polycystic ovary syndrome. This irregular bleeding may also be heavy. Hormonal treatments are commonly given to these women, but there is insufficient evidence to recommend whether progestogens alone or progestogens in combination with oestrogen are most effective for irregular uterine bleeding associated with infrequent or no ovulation.

Birth control pills with 20 µg estrogen versus more than 20 µg estrogen

Concerns about safety have led to making birth control pills with less of the hormone estrogen. Pills with less estrogen might not work as well to prevent pregnancy and could cause bleeding problems. This review looked at studies that compared pills with 20 µg ethinyl estradiol versus pills that have more estrogen.

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Summaries for consumers

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes

Diethylstilbestrol during pregnancy poses serious long‐term risks for those exposed in the womb and offers no known benefit for mothers and children.

Progestogens with or without oestrogen for irregular menstrual bleeding

Irregular bleeding associated with infrequent or no ovulation occurs most commonly in adolescents and in women approaching the menopause. It may also occur in those with polycystic ovary syndrome. This irregular bleeding may also be heavy. Hormonal treatments are commonly given to these women, but there is insufficient evidence to recommend whether progestogens alone or progestogens in combination with oestrogen are most effective for irregular uterine bleeding associated with infrequent or no ovulation.

Birth control pills with 20 µg estrogen versus more than 20 µg estrogen

Concerns about safety have led to making birth control pills with less of the hormone estrogen. Pills with less estrogen might not work as well to prevent pregnancy and could cause bleeding problems. This review looked at studies that compared pills with 20 µg ethinyl estradiol versus pills that have more estrogen.

See all (184)

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