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Chlorhexidine

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Into the mouth

Treats gingivitis and periodontitis (teeth and gum disease)… Read more

Brand names include: Periochip

On the skin

Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. It is used to clean the skin after an injury, before surgery, or… Read more

Brand names include: Antiseptic Skin Cleanser, Aplicare Antiseptic Chlorhexidine Gluconate

Oral route

Chlorhexidine is used to treat gingivitis. It helps to reduce the inflammation (redness) and swelling of your gums and to reduce gum bleeding. Gingivitis… Read more

Brand names include: Paroex, Peridex

Periodontal route

Chlorhexidine is used to help treat periodontal disease (a disease of your gums), which is caused by bacteria growing beneath the gum line. Chlorhexidine… Read more

Drug classes About this
Antibacterial, Antibacterial Cleansing Agent, Wound Care Agent

What works? Research summarized

Evidence reviews

Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding group B streptococcal and HIV)

Bacteria live in women's vaginas and generally cause no problems. Very occasionally they infect the placenta during labour and can pass to the baby, causing an infection. These infections can occasionally make the baby very ill and very occasionally the baby might die.

Antibacterial chlorhexidine applied to the vagina during labour to prevent early‐onset group B streptococcal infection in the newborn

There is no evidence to show that washing the vagina with the antibacterial liquid chlorhexidine or using a chlorhexidine gel during labour reduces group B β‐hemolytic streptococcal (GBS) infections in babies.

Antiseptic treatment (chlorhexidine) to prevent tooth decay in children and young people

This review examined the effectiveness of varnishes and gels containing chlorhexidine in preventing tooth decay in children and young people.

See all (161)

Summaries for consumers

Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding group B streptococcal and HIV)

Bacteria live in women's vaginas and generally cause no problems. Very occasionally they infect the placenta during labour and can pass to the baby, causing an infection. These infections can occasionally make the baby very ill and very occasionally the baby might die.

Antibacterial chlorhexidine applied to the vagina during labour to prevent early‐onset group B streptococcal infection in the newborn

There is no evidence to show that washing the vagina with the antibacterial liquid chlorhexidine or using a chlorhexidine gel during labour reduces group B β‐hemolytic streptococcal (GBS) infections in babies.

Antiseptic treatment (chlorhexidine) to prevent tooth decay in children and young people

This review examined the effectiveness of varnishes and gels containing chlorhexidine in preventing tooth decay in children and young people.

See all (29)

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