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Somatropin (Genotropin) for Subcutaneous Injection: The Treatment of Short Stature Associated with Turner Syndrome in Patients Whose Epiphyses are not Closed [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jan.

5CONCLUSIONS

Based on the findings of two systematic reviews, it appears that somatropin treatment results in greater and more rapid gains in height, including final height, compared with no treatment. However, whether QoL is improved in those treated with somatropin compared with those not treated is uncertain. Genotropin is one of several somatropin products approved by Health Canada for the treatment of short stature associated with TS; others include Humatrope, Nutropin, and Saizen. There is insufficient evidence on the comparative efficacy and safety of the somatropin products for the treatment of short stature associated with TS. In clinical practice, product selection is generally based upon patient and/or parent preference in consultation with the clinician.

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Cover of Somatropin (Genotropin) for Subcutaneous Injection
Somatropin (Genotropin) for Subcutaneous Injection: The Treatment of Short Stature Associated with Turner Syndrome in Patients Whose Epiphyses are not Closed [Internet].

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