PubMed Health. A service of the National Library of Medicine, National Institutes of Health.

Somatropin (Genotropin) for Subcutaneous Injection: The Treatment of Short Stature Associated with Turner Syndrome in Patients Whose Epiphyses are not Closed [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jan.

ABBREVIATIONS

AACE

American Association of Clinical Endocrinologists

AE

adverse event

AUC

area under the concentration curve

AUEC

area under the effective concentration curve

CADTH

Canadian Agency for Drugs and Technologies in Health

CDR

Common Drug Review

CI

confidence interval

Cmax

maximum plasma concentration of drug

CRI

chronic renal insufficiency

ES

estrogen

E. coli

Escherichia coli

Emax

maximum effect of drug

FH

final height

GEN

Genotropin

GHD

growth hormone deficiency

h

hour

HCP

host cell proteins

HRQoL

health-related quality of life

Height SDS

height standard deviation score

HV

height velocity

HVSDS

height velocity standard deviation score

IGF-1

insulin-like growth factor-1

im

intramuscular

ISS

idiopathic short stature

IU

international units

kg

kilograms

L

litre

lyo

lyophilized

MA

meta-analysis

max

maximum

mcg

microgram

mg

milligrams

mL

millilitres

NR

not reported

PECP

periplasmic Escherichia coli peptides

PWS

Prader-Willi syndrome

QoL

quality of life

RCT

randomized controlled trial

rhGH

recombinant human growth hormone

SAE

serious adverse event

sc

subcutaneous

SD

standard deviation

SDS

standard deviation score

SGA

small for gestational age

SHOX

short-stature homeobox-containing gene

Soma

somatropin

T1/2

drug half-life

Tmax

time to reach maximum concentration of the drug

TS

Turner syndrome

WDAE

withdrawal due to adverse event

WMD

weighted mean difference

Copyright © CADTH 2014.

You are permitted to make copies of this document for non-commercial purposes, provided it is not modified when reproduced and appropriate credit is given to CADTH. You may not otherwise copy, modify, translate, post on a website, store electronically, republish, or redistribute any material from this document in any form or by any means without the prior written permission of CADTH.

Please contact CADTH’s Vice-President of Corporate Services at ac.htdac@secivresetaroproc with any inquiries about this notice or other legal matters relating to CADTH’s services.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial- NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Cover of Somatropin (Genotropin) for Subcutaneous Injection
Somatropin (Genotropin) for Subcutaneous Injection: The Treatment of Short Stature Associated with Turner Syndrome in Patients Whose Epiphyses are not Closed [Internet].

PubMed Health Blog...

read all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...