Table 19Body of evidence for subcutaneous immunotherapy affecting combined symptom- medication scores in children and adolescents)

StudyAllergenComparatorNumber of ParticipantsRisk of BiasDirection of ChangeDirectnessMagnitude of Effect
Altintas 199950Dust miteSCIT-Adsorbed Al
SCIT-Adsorbed Ca
SCIT-aqueous
Placebo
35High+DirectStrong
Kuna 2011112AlternariaSCIT
Placebo
50Medium+DirectStrong

+ = positive; Al = aluminum; Ca = calcium; SCIT = subcutaneous immunotherapy

From: Results

Cover of Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma: Comparative Effectiveness Review
Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma: Comparative Effectiveness Review [Internet].
Comparative Effectiveness Reviews, No. 111.
Lin SY, Erekosima N, Suarez-Cuervo C, et al.

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