Figure B shows the algorithm on how the studies were distributed first by intervention (SCIT, SLIT, SLIT vs SCIT), then by disease Asthma or Rhinitis/rhinoconjunctivitis and finally by allergen. The allergens were stratified first between seasonal and perennial and within each category the different allergens were defined; Seasonal (trees, grass, weeds and molds) and Perennial (domestic animals, cockroach, dust mite and mold).

Figure BAlgorithm for the approach and classification of the studies

SCIT = subcutaneous immunotherapy; SIT = allergen specific immunotherapy; SLIT = sublingual immunotherapy

From: Executive Summary

Cover of Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma: Comparative Effectiveness Review
Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma: Comparative Effectiveness Review [Internet].
Comparative Effectiveness Reviews, No. 111.
Lin SY, Erekosima N, Suarez-Cuervo C, et al.

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