Figure F-161 is titled “Rate of diarrhea for SSRIs compared with placebo.” The figure displays a forest plot reporting the risk difference of diarrhea stratified by fluoxetine compared with placebo and sertraline compared with placebo. The forest plot depicts that a higher rate of dry mouth occurred among patients treated with fluoxetine (1 trial, risk difference 0.24, 95% CI 0.01 to 0.47) and sertraline (5 trials, risk difference 0.12, 95% CI 0.07 to 0.17, I2 = 0.0%). Overall there was a 13% higher rate of diarrhea related to SSRIs than placebo (risk difference 0.13, 95% CI 0.08 to 0.17, I2 = 0.0%).

Figure F-161Rate of diarrhea for SSRIs compared with placebo

Timing of outcome assessment: 5 weeks (van der Kolk, 1994); 10 weeks (Panahi, 2001), 12 weeks (Davidson, 2006; Davidson, 2001; Brady, 2000; Friedman, 2007).

From: Appendix F, Meta-Analysis

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)
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