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Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

Subintimal angioplasty for chronic arterial occlusive disease: a systematic review

Review published: 2012.

Bibliographic details: Li XX, Lu XW, Ye KC, Jiang ME.  Subintimal angioplasty for chronic arterial occlusive disease: a systematic review. National Medical Journal of China 2012; 92(21): 1486-1491. [PubMed: 22944036]

Abstract

OBJECTIVE: To evaluate the clinical effectiveness of subintimal angioplasty in treating chronic arterial occlusive disease of lower extremity.

METHODS: Eligible studies concerning treatment by subintimal angioplasty in patients with arterial occlusive disease of lower extremity were identified from electronic database, cross-reference search and relative articles. The study quality and data extraction of all relevant articles were assessed by three independent reviewers. The study endpoints were technical success, primary patency, limb salvage, and complications.

RESULTS: A total of 352 studies were selected for comprehensive review. Fourteen studies including a total of 2350 patients matched the selection criteria. According to whether selective using of re-entry catheter were used or not, the technical success rates were 96.4% and 87% (P < 0.01). Limb salvage rate was 90.5% and 81.5% at 6 and 12 months respectively. Depending on whether preoperative use of anti-platelet drug, primary patency rate was 91% and 68.5% at 6 months respectively (P < 0.01). The complication rate was 8.25% without serious complications.

CONCLUSION: This Meta-analysis suggests that subintimal angioplasty is a safe and effective method in treating chronic arterial occlusive disease of lower extremity with high technical success rate and limb salvage, and low serious complications. Selective using of re-entry devices and preoperative anti-platelet drug can improve the technical success rate and primary patency rate significantly. Despite the high rate of technical and clinical success of the procedure, randomized contrast trials and long-term follow-up results are required to confirm the efficacy of these results.

CRD has determined that this article meets the DARE scientific quality criteria for a systematic review.

Copyright © 2014 University of York.

PMID: 22944036

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