Table 5.5Evidence profile for diagnostic test accuracy of prolonged preterm prelabour rupture of membranes (> 24 hours) for predicting early-onset neonatal infection (in the first 7 days of life) in extremely premature or low birthweight babies (< 28 weeks’ gestation at birth or birthweight < 1000g)

Number of studiesNumber of babiesSensitivity (95% confidence interval)Specificity (95% confidence interval)Positive likelihood ratio (95% confidence interval)Negative likelihood ratio (95% confidence interval)Quality
Prolonged preterm prelabour rupture of membranes
1
(Ronnestad 2005)
46240.0
(22.4 to 57.5)*
77.1
(73.1 to 81.1)*
1.75
(1.09 to 2.80)*
0.78
(0.58 to 1.05)*
Moderate
*

Calculated by the NCC-WCH technical team from data reported in the article

See the complete GRADE Table J 5.5

From: 5, Risk factors for infection and clinical indicators of possible infection

Cover of Antibiotics for Early-Onset Neonatal Infection
Antibiotics for Early-Onset Neonatal Infection: Antibiotics for the Prevention and Treatment of Early-Onset Neonatal Infection.
NICE Clinical Guidelines, No. 149.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2012 Aug.
Copyright © 2012, National Collaborating Centre for Women’s and Children’s Health.

No part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.