Table 5-20Risk of major bleeding, by type of surgery, from the nil arm of RCTs

Number of patients with an eventSample SizeIncidenceIncidence Lower 95% CLIncidence Upper 95% CL
Major Bleeding
Orthopaedic (Elective Hip))12,39,151,153,249,261,380,410,421,587,650,659,684251172%1%2%
Orthopaedic (Hip fracture))74,176,178,248,312,316,381,385,463,464,533,704,710297723%2%5%
Orthopaedic (Elective knee)388,436,443,69942742%1%4%
Orthopaedic (Mixed) 7,69,521,700058
Vascular 615019
Not known93,337,364,365,71822541%0%3%

From: 5, Risk, risk reduction and harm

Cover of Venous Thromboembolism
Venous Thromboembolism: Reducing the Risk of Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Embolism) in Patients Admitted to Hospital.
NICE Clinical Guidelines, No. 92.
National Clinical Guideline Centre – Acute and Chronic Conditions (UK).
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