Intervention(s)Comparison(s)Intervention favoured
Prophylaxis vs no prophylaxis
UFHNilNot sig--
Asp(HD) +/− antiplateletsNilNot sigNo events-
Single prophylaxis vs single
UFHLMWHNot sig--
Double prophylaxis vs single
Cost Effectiveness
There is no relevant cost-effectiveness evidence specifically for this population subgroup.

The prophylaxis strategy which is significantly more effective in reducing DVT or PE; or resulting in significantly less major bleeding is stated in bold.

Not sig - not statistically significant difference; ‘-’ = not reported; no events – nobody in the study had the outcome. MB = Major bleeding

From: 20, Spinal injury

Cover of Venous Thromboembolism
Venous Thromboembolism: Reducing the Risk of Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Embolism) in Patients Admitted to Hospital.
NICE Clinical Guidelines, No. 92.
National Clinical Guideline Centre – Acute and Chronic Conditions (UK).
Copyright © 2010, National Clinical Guideline Centre - Acute and Chronic Conditions.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of National Clinical Guideline Centre - Acute and Chronic Conditions to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.