Home > Search Results

Results: 9

Colorectal Cancer: The Diagnosis and Management of Colorectal Cancer

Colorectal Cancer: The Diagnosis and Management of Colorectal Cancer

NICE Clinical Guidelines - National Collaborating Centre for Cancer (UK)

Version: November 2011

Key priorities for implementation

Offer colonoscopy to patients without major comorbidity, to confirm a diagnosis of colorectal cancer. If a lesion suspicious of cancer is detected, perform a biopsy to obtain histological proof of diagnosis, unless it is contraindicated (for example, patients with a blood clotting disorder).

List of all recommendations

Advise the patient that more than one investigation may be necessary to confirm or exclude a diagnosis of colorectal cancer.

Management of metastatic disease

Approximately 25% of patients with colorectal cancer have metastatic disease at the time of initial presentation and it is thought that their outcome is often worse than for those patients who develop metachronous metastatic disease following apparently curative resection of their primary tumour.

Management of local disease

The National Bowel Cancer Audit Programme (NBOCAP, 2005) 8 www.nbocap.org.uk report recognised that the positive circumferential resection margin rates for anterior resection by total mesorectal excision (TME) and abdomino-perineal resection (APR) were 6.5% and 15.6%, respectively (assuming all missing values were negative). The inference from these results is that many patients with rectal cancer are understaged prior to surgery and/or the chosen treatment strategy was either inappropriate or suboptimal.

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...