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More is not necessarily better

A popular misconception is that if a treatment is good then more of it must be better. This is simply not true – indeed more can be worse. Finding the ‘right’ dose – where benefits are high and adverse effects (side-effects) are low – is a challenge common to all treatments. As the dose is increased, beneficial effects reach a plateau, but adverse effects usually increase. So ‘more’ may decrease the actual benefit, or even cause overall harm.

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