Table H.5.3GRADE findings for antenatal diagnosis of placenta accreta compared with no antenatal diagnosis (neonatal outcomes)

Quality assessmentSummary of findings
No. of patientsEffect
No. of studiesDesignLimitationsInconsistencyIndirectnessImprecisionOther considerationsAntenatal diagnosis of placenta accretaNo antenatal diagnosis of placenta accretaRelative (95% CI)Absolute (95% CI)Quality
Neonatal intensive care unit [NICU] admission
1 study

(Warshak et al., 2009)
observational studySerious1no serious inconsistencySerious2,3serious4none50/62

(80%)
19/37

(51%)
RR 1.57

(1.16 to 2.28)*
292 more per 1000

(from 102 more to 437 more)*
Very low
NICU length of stay
1 study

(Warshak et al., 2009)
observational studySerious1no serious inconsistencyserious1,3no serious imprecisionnone9.8 days

(SD 2.5)

n = 62
6.3 days

(SD 3.5)

n = 37
Not calculableMD 3.50 higher

(2.30 lower to 4.70 higher)

p = 0.13
Very low
1

Small size study with low statistical power

2

15% of the total population (n = 15/99) had no previous CS.

3

71 out of the total population (n = 71/99) had placenta praevia in their current pregnancy.

4

Wide CI

*

Calculated by NCC-WCH technical team

From: Appendix H, GRADE tables

Cover of Caesarean Section
Caesarean Section.
NICE Clinical Guidelines, No. 132.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2011 Nov.
Copyright © 2011, National Collaborating Centre for Women's and Children's Health.

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