Table 70Saline washout (once a day) vs. no washout – Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Catheter replacement per 100 days of catheterisation1761RCTSerious limitations(a, b, c)No serious inconsistencyNo serious indirectnessSerious imprecision(d)
Encrustations and blockages0RCT
Patient preference and comfort0RCT
Symptomatic UTI0RCT

Crossover trial. Sequence generation and allocation concealment not clear.


23 patients participated in full duration of trial, but 32 patients (crossover and partial crossover patients) included in analysis.


Blinding not reported.


Wide confidence intervals crossing MID. This makes it difficult to know the true effect size for this outcome.

From: 10, Long term urinary catheters

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Infection: Prevention and Control of Healthcare-Associated Infections in Primary and Community Care: Partial Update of NICE Clinical Guideline 2.
NICE Clinical Guidelines, No. 139.
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