Table 12Hyperlipidemia: strength of evidence for collaborative care intervention

InterventionNumber of Trials; Subjects (Analyzed)OutcomeRisk of BiasConsistencyDirectnessPrecisionMagnitude of Effect and Strength of Evidence
Hyperlipidemia: Collaborative care vs. usual care1; 329
(117 on lipid- lowering meds)
Medication adherenceRCT
Medium
UnknownDirectImpreciseNo sig diff between groups for percentage of days nonadherent (28.8% vs. 27.7%) or difference in change in adherence (−0.2%) over 12 months, pharmacy refill
Insufficient

Abbreviations: diff = difference; RCT = randomized controlled trials; sig = significant; vs. = versus.

From: Results

Cover of Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness)
Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness).
Evidence Reports/Technology Assessments, No. 208.4.
Viswanathan M, Golin CE, Jones CD, et al.

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